SCHEMBL7397351

SCHEMBL7397351

N=C(N)c1ccc(CCCC[C@H]2C[C@@H](O)CC(=O)O2)cc1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.40
PRKCD Q05655 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7399030 1.00 PRKCA (0.40) PRKCAPRKCD
SCHEMBL7397347 1.00 PRKCA (0.40) PRKCAPRKCD
SCHEMBL7398589 0.88 PRKCA (0.41) PRKCAPRKCD
SCHEMBL7399033 0.88 PRKCA (0.41) PRKCAPRKCD
SCHEMBL7403999 0.88 PRKCA (0.41) PRKCAPRKCD
SCHEMBL7398538 0.85 PRKCA (0.37) PRKCAPRKCD
SCHEMBL7398536 0.85 PRKCA (0.37) PRKCAPRKCD
SCHEMBL7398691 0.84 F2 (0.43) PRKCAPRKCD
SCHEMBL7392199 0.84 SPHK1 (0.40) PRKCAPRKCD
SCHEMBL7400741 0.84 F2 (0.43) PRKCAPRKCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1994000424-A1 PHENYL AMIDINE ALKANOIC ACIDS AND LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1994-01-06 WO claimed
US-5646183-A Phenyl amidine alkanoic acids useful as platelet aggregation inhibitors G. D. SEARLE & CO. (US) 1997-07-08 US disclosed
US-5612355-A Phenyl amidine lactones useful as platelet aggregation inhibitors G. D. SEARLE & CO. (US) 1997-03-18 US disclosed
WO-1994000424-A1 PHENYL AMIDINE ALKANOIC ACIDS AND LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1994-01-06 WO disclosed