Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.46 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | F2R | P25116 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7385931 | 0.99 | CACNA2D1 (0.45) | CACNA2D1CACNA1BCACNB1ITGB3ITGA2B | |
| SCHEMBL7367467 | 0.84 | DRD2 (0.57) | DRD2DRD3 | |
| SCHEMBL7394485 | 0.80 | S1PR1 (0.54) | ITGB3ITGA2BDRD2HDAC1ADRB2 | |
| Hydrochloric Acid SCHEMBL7395305 | 0.79 | S1PR1 (0.53) | ITGB3ITGA2BDRD2HDAC1ADRB2 | |
| SCHEMBL7390623 | 0.78 | PRMT1 (0.44) | ITGB3ITGA2BDRD2HDAC1DRD3 | |
| SCHEMBL7390619 | 0.78 | PRMT1 (0.44) | ITGB3ITGA2BDRD2HDAC1DRD3 | |
| SCHEMBL27402876 | 0.78 | DRD2 (0.49) | ITGB3ITGA2BDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7393330 | 0.77 | PRMT1 (0.43) | ITGB3ITGA2BDRD2HDAC1DRD3 | |
| Hydrochloric Acid SCHEMBL7392502 | 0.76 | S1PR1 (0.50) | ITGB3ITGA2BDRD2HDAC1ADRB2 | |
| SCHEMBL8415959 | 0.76 | CACNA2D1 (0.43) | CACNA2D1CACNA1BCACNB1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587134-A2 | Cyclic urea derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-03-16 | — | — | EP | claimed |
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |
| EP-0587134-A2 | Cyclic urea derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-03-16 | — | — | EP | disclosed |