Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 12/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 8/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | PPOX | P50336 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | ABL2 | P42684 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28148276 | 0.77 | GSK3B (0.45) | WEE1CHEK1GRM5PARP1TDP2 | |
| SCHEMBL25169424 | 0.74 | PPOX (0.45) | WEE1CHEK1GRM5PPOXPARP1 | |
| SCHEMBL32089673 | 0.71 | GSK3B (0.43) | GRM5PPOXPARP1PRKD3EGFR | |
| SCHEMBL1081008 | 0.71 | GSK3B (0.43) | GRM5PPOXPARP1PRKD3EGFR | |
| SCHEMBL15323077 | 0.70 | WEE1 (0.49) | WEE1CHEK1TDP2PRKD3ABL1 | |
| SCHEMBL29710128 | 0.70 | GRM5 (0.46) | WEE1CHEK1GRM5PPOXPARP1 | |
| SCHEMBL9279015 | 0.70 | GRM5 (0.46) | WEE1CHEK1GRM5PPOXPARP1 | |
| SCHEMBL7390244 | 0.69 | CA12 (0.36) | GRM5TDP2 | |
| SCHEMBL28920768 | 0.69 | GRM5 (0.44) | WEE1CHEK1GRM5PPOXPARP1 | |
| SCHEMBL29578942 | 0.69 | GSK3B (0.52) | GRM5PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179026-A4 | BRANCHED AND HYPERBRANCHED POLYETHERIMIDES FROM STABLE A1Bn, AB, AA, AND BB MONOMERS; AM ENDCAPPING AGENTS | UNIV ILLINOIS (US) | 2003-04-02 | — | — | EP | disclosed |
| EP-1179026-A1 | BRANCHED AND HYPERBRANCHED POLYETHERIMIDES FROM STABLE A1Bn, AB, AA, AND BB MONOMERS; AM ENDCAPPING AGENTS | The Board of Trustees for the University of Illinois (US) | 2002-02-13 | — | — | EP | disclosed |
| US-6333390-B1 | HIGH SOLUBILITY AND LOW VISCOSITY, THERMALLY AND CHEMICALLY STABLE, REACTING AN AMINO-PHENOL WITH AN AROMATIC ANHYDRIDE, MIXING THE RESULTING ARYLIMIDE WITH A SILYL ELECTROPHILE AND A BASE, | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2001-12-25 | — | — | US | disclosed |
| WO-2000026267-A9 | BRANCHED AND HYPERBRANCHED POLYETHERIMIDES FROM STABLE A1Bn, AB, AA, AND BB MONOMERS; AM ENDCAPPING AGENTS | UNIV ILLINOIS (US) | 2000-10-19 | — | — | WO | disclosed |
| WO-2000026267-A1 | BRANCHED AND HYPERBRANCHED POLYETHERIMIDES FROM STABLE A1Bn, AB, AA, AND BB MONOMERS; AM ENDCAPPING AGENTS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2000-05-11 | — | — | WO | disclosed |