Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 6/20 | 0.73 |
| ▸ | MGAM | O43451 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | SI | P14410 | 1/20 | 0.65 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.65 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.61 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.53 |
| ▸ | SCD | O00767 | 1/20 | 0.53 |
| ▸ | METAP2 | P50579 | 1/20 | 0.51 |
| ▸ | METAP1 | P53582 | 1/20 | 0.51 |
| ▸ | CBFB | Q13951 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7393557 | 0.83 | GUSB (0.79) | GUSBMGAMGAASIMGAM2 | |
| SCHEMBL3337332 | 0.82 | METAP2 (0.62) | GUSBGAAHPSEMETAP2METAP1 | |
| SCHEMBL3339892 | 0.82 | GUSB (0.73) | GUSBMGAMGAASIMGAM2 | |
| Hydrochloric Acid SCHEMBL10736606 | 0.81 | GUSB (0.77) | GUSBMGAMGAASIMGAM2 | |
| SCHEMBL24075313 | 0.80 | HPSE (0.61) | GUSBGAAHPSESCDMETAP2 | |
| SCHEMBL7395100 | 0.80 | KDM4E (0.67) | MGAMGAASIMGAM2PTPN1 | |
| SCHEMBL24075254 | 0.79 | GUSB (0.50) | GUSBAMY1AHPSESCDMETAP2 | |
| SCHEMBL28179657 | 0.79 | HPSE (0.60) | GUSBAMY1AHPSEMETAP2METAP1 | |
| SCHEMBL7396446 | 0.78 | MEN1 (0.70) | MGAMGAASIMGAM2AMY1A | |
| SCHEMBL7396441 | 0.78 | KDM4E (0.54) | GUSBMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066526-A1 | ESTER DERIVATIVES OF DIMETHYLPROPIONIC ACID AND PHARMACETUICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2001-09-13 | — | — | WO | disclosed |
| EP-1132381-A1 | Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2001-09-12 | — | — | EP | disclosed |