Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.62 |
| ▸ | METAP1 | P53582 | 1/20 | 0.62 |
| ▸ | CBFB | Q13951 | 1/20 | 0.62 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24075313 | 0.97 | HPSE (0.61) | METAP2METAP1CBFBHPSENPC1 | |
| SCHEMBL25722414 | 0.86 | HPSE (0.64) | METAP2METAP1CBFBHPSENPC1 | |
| SCHEMBL3132123 | 0.85 | NPC1 (0.68) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL24075259 | 0.84 | GUSB (0.76) | METAP2METAP1CBFBHPSENPC1 | |
| SCHEMBL4494716 | 0.84 | NPC1 (0.68) | METAP2METAP1CBFBNPC1RAB9A | |
| SCHEMBL24075251 | 0.83 | METAP2 (0.56) | METAP2METAP1CBFBHPSENPC1 | |
| SCHEMBL21011385 | 0.83 | NPC1 (0.70) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL903717 | 0.83 | NPC1 (0.66) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL7393557 | 0.83 | GUSB (0.79) | HPSEGAAGUSB | |
| SCHEMBL3333916 | 0.83 | GUSB (0.79) | HPSENPC1RAB9AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251760-B1 | Rubber composition | BRIDGESTONE CORP (JP) | 1994-01-26 | — | — | EP | claimed |
| US-5140055-A | Improved high speed grip performance | BRIDGESTONE CORPORATION (JP) | 1992-08-18 | — | — | US | claimed |
| CN-114989094-B | Method for synthesizing benzimidazole derivative by visible light catalysis | 云南民族大学 | 2023-09-29 | — | — | CN | disclosed |
| CN-114989094-A | Method for synthesizing benzimidazole derivative by visible light catalysis | 云南民族大学 | 2022-09-02 | — | — | CN | disclosed |
| CN-108043442-B | Carbon-supported ruthenium nano material, preparation method thereof and application of carbon-supported ruthenium nano material in catalyzing reaction of alcohol and aromatic diamine | 苏州大学 | 2021-03-19 | — | — | CN | disclosed |
| US-9169282-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2015-10-27 | — | — | US | disclosed |
| US-9169282-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2015-10-27 | — | — | US | disclosed |
| US-8198307-B2 | Imidazole derivatives having aryl piperidine substituent, method for preparation thereof and pharmaceutical compositions containing same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2012-06-12 | — | — | US | disclosed |
| US-20110284799-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-11-24 | — | — | US | disclosed |
| US-20110284799-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-11-24 | — | — | US | disclosed |
| US-20110269071-A1 | ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, CHEMICAL AMPLIFICATION RESIST COMPOSITION, AND RESIST FILM AND PATTERN FORMING METHOD USING THE COMPOSITION | FUJIFILM CORPORATION (JP) | 2011-11-03 | — | — | US | disclosed |
| WO-2010086089-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2010-08-05 | — | — | WO | disclosed |
| US-20100145054-A1 | IMIDAZOLE DERIVATIVES HAVING ARYL PIPERIDINE SUBSTITUENT, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-10 | — | — | US | disclosed |
| EP-0251760-B1 | Rubber composition | BRIDGESTONE CORP (JP) | 1994-01-26 | — | — | EP | disclosed |
| US-5140055-A | Improved high speed grip performance | BRIDGESTONE CORPORATION (JP) | 1992-08-18 | — | — | US | disclosed |
| EP-0251760-A2 | Rubber composition | Bridgestone Corporation (JP) | 1988-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110284799-A1 | METAL COMPLEXES | SOD1, AP1M1, AP3M1 | METAP2 1998/4885METAP1 2748/4885CBFB 790/4885 |
| US-20100145054-A1 | IMIDAZOLE DERIVATIVES HAVING ARYL PIPERIDINE SUBSTITUENT, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | TYR, MCHR1, MCHR2 | METAP2 899/4885METAP1 672/4885CBFB 2926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.