Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 4/20 | 0.38 |
| ▸ | CTSL | P07711 | 3/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
| ▸ | IL2RA | P01589 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | IL2 | P60568 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9002928 | 0.89 | F2 (0.47) | F2PRSS1ITGB3ITGA2BTPSAB1 | |
| Hydrochloric Acid SCHEMBL9003001 | 0.89 | F2 (0.48) | F2PRSS1ITGB3ITGA2BTPSAB1 | |
| SCHEMBL7393871 | 0.88 | CYP1A2 (0.41) | F2BCHEACHECACNA1FCACNA1D | |
| SCHEMBL9002775 | 0.85 | BCHE (0.39) | F2BCHEACHECACNA1FCACNA1D | |
| SCHEMBL9002887 | 0.83 | F2 (0.48) | F2BCHEACHECACNA1FCACNA1D | |
| Hydrochloric Acid SCHEMBL9002599 | 0.83 | F2 (0.49) | F2BCHEACHECACNA1FCACNA1D | |
| SCHEMBL9003040 | 0.83 | F2 (0.47) | F2PRSS1ITGB3ITGA2BTPSAB1 | |
| SCHEMBL8947637 | 0.82 | F2 (0.62) | F2 | |
| SCHEMBL9002921 | 0.82 | CASP1 (0.40) | F2CTSKCTSLCTSSCTSB | |
| SCHEMBL27405085 | 0.82 | TPSAB1 (0.46) | F2BCHEACHECACNA1FCACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559232-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0641779-A1 | Novel 1-amidinopiperdines and 4-amidinomorpholines as aggregation inhibitions | F. HOFFMANN-LA ROCHE AG (CH) | 1995-03-08 | — | — | EP | disclosed |