Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.47 |
| ▸ | EDNRB | P24530 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394509 | 0.90 | CTSD (0.56) | KDM4EHSD17B10ALDH1A1SIRT2SIRT1 | |
| SCHEMBL7385375 | 0.87 | SIRT2 (0.52) | KDM4EHSD17B10ALDH1A1SIRT2SIRT1 | |
| SCHEMBL7387135 | 0.84 | SIRT2 (0.52) | KDM4EHSD17B10ALDH1A1SIRT2SIRT1 | |
| SCHEMBL7394378 | 0.83 | ALDH1A1 (0.63) | KDM4EALDH1A1TP53HPGDHTT | |
| SCHEMBL14646191 | 0.82 | HSD17B10 (0.94) | KDM4EHSD17B10ALDH1A1HPGDHTT | |
| SCHEMBL7394081 | 0.81 | TP53 (0.54) | KDM4EHSD17B10ALDH1A1TP53HPGD | |
| SCHEMBL7389782 | 0.81 | KDM4E (0.61) | KDM4EHSD17B10ALDH1A1SIRT2SIRT1 | |
| SCHEMBL7394420 | 0.81 | SIRT2 (0.55) | KDM4EHSD17B10ALDH1A1SIRT2SIRT1 | |
| SCHEMBL7394207 | 0.81 | HPGD (0.49) | KDM4EHSD17B10ALDH1A1SIRT2SIRT1 | |
| SCHEMBL7385813 | 0.80 | PRKACA (0.55) | KDM4EHSD17B10ALDH1A1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130333-A | VISION DEFECTS; CARDIOVASCULAR DISORDERS | MONSANTO COMPANY (US) | 2000-10-10 | — | — | US | disclosed |