Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.35 |
| ▸ | CPN1 | P15169 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9003065 | 0.99 | F2 (0.35) | F2PRSS1CPN1CPB2LMNA | |
| SCHEMBL7391071 | 0.88 | TPSAB1 (0.40) | F2PRSS1 | |
| Hydrochloric Acid SCHEMBL9002664 | 0.87 | TPSAB1 (0.40) | F2PRSS1 | |
| SCHEMBL7294941 | 0.84 | F2 (0.34) | F2PRSS1CPN1CPB2 | |
| SCHEMBL7386668 | 0.83 | ITGB3 (0.34) | F2PRSS1CPN1CPB2LMNA | |
| Hydrochloric Acid SCHEMBL9002731 | 0.83 | ITGB3 (0.34) | F2PRSS1CPN1CPB2LMNA | |
| SCHEMBL9003224 | 0.83 | F2 (0.42) | F2PRSS1ITGB3ITGA2B | |
| SCHEMBL7390168 | 0.83 | ACE (0.33) | F2PRSS1CPN1CPB2ITGB3 | |
| Hydrochloric Acid SCHEMBL9003085 | 0.82 | F2 (0.42) | F2PRSS1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL9003035 | 0.82 | ACE (0.33) | F2PRSS1CPN1CPB2ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559232-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0641779-A1 | Novel 1-amidinopiperdines and 4-amidinomorpholines as aggregation inhibitions | F. HOFFMANN-LA ROCHE AG (CH) | 1995-03-08 | — | — | EP | disclosed |