Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683571 | 0.81 | GRIK1 (0.37) | HTR2AHRH1PGRADRA2AADRA2B | |
| SCHEMBL1116503 | 0.79 | CA12 (0.33) | — | |
| SCHEMBL30053640 | 0.77 | CHRNB2 (0.32) | — | |
| SCHEMBL22288093 | 0.77 | — | — | |
| SCHEMBL19886164 | 0.77 | FDPS (0.37) | HTR2AHRH1PGRADRA2AADRA2B | |
| SCHEMBL28616559 | 0.77 | HTR2A (0.40) | HTR2AHRH1PGRADRA2AADRA2B | |
| SCHEMBL155767 | 0.77 | FDPS (0.37) | HTR2AHRH1PGRADRA2AADRA2B | |
| SCHEMBL3785080 | 0.77 | FDPS (0.37) | HTR2AHRH1PGRADRA2AADRA2B | |
| SCHEMBL20521476 | 0.75 | OR51E2 (0.36) | HTR2AHRH1PGRADRA2AADRA2B | |
| SCHEMBL305175 | 0.75 | OR51E2 (0.36) | HTR2AHRH1PGRADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000055156-A1 | SUBSTITUTED AROMATIC AMIDINE DERIVATIVE AND MEDICINAL COMPOSITION COMPRISING THE SAME | C & C RESEARCH LABORATORIES (KR) | 2000-09-21 | — | — | WO | claimed |
| WO-2000055156-A1 | SUBSTITUTED AROMATIC AMIDINE DERIVATIVE AND MEDICINAL COMPOSITION COMPRISING THE SAME | C & C RESEARCH LABORATORIES (KR) | 2000-09-21 | — | — | WO | disclosed |