Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPK9 | P45984 | 9/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 9/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4961217 | 0.78 | L3MBTL1 (0.81) | L3MBTL1GAAALDH1A1PKMMAPT | |
| SCHEMBL18292261 | 0.75 | L3MBTL1 (0.64) | L3MBTL1GAAALDH1A1PKMMAPT | |
| SCHEMBL9455568 | 0.73 | MAPK9 (0.58) | ALDH1A1MAPTLMNAKDM4EMAPK9 | |
| SCHEMBL7688613 | 0.73 | L3MBTL1 (1.00) | L3MBTL1GAAALDH1A1PKMMAPT | |
| SCHEMBL7692277 | 0.72 | GAA (0.67) | L3MBTL1GAAALDH1A1PKMMAPT | |
| SCHEMBL7395747 | 0.71 | MAPK10 (0.66) | ALDH1A1MAPTLMNAKDM4EMAPK9 | |
| SCHEMBL7396493 | 0.69 | MAPK10 (0.64) | ALDH1A1MAPTLMNAKDM4EMAPK9 | |
| SCHEMBL7400010 | 0.69 | HPGD (0.59) | GAAALDH1A1MAPTLMNAMAPK9 | |
| SCHEMBL1519025 | 0.69 | MAPK10 (1.00) | ALDH1A1MAPTLMNAKDM4EMAPK9 | |
| SCHEMBL9455629 | 0.68 | MAPT (0.57) | ALDH1A1MAPTLMNAMAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1110957-A1 | Benzazole derivatives and their use as JNK modulators | Applied Research Systems ARS Holding N.V. (AN) | 2001-06-27 | — | — | EP | claimed |
| EP-1110957-A1 | Benzazole derivatives and their use as JNK modulators | Applied Research Systems ARS Holding N.V. (AN) | 2001-06-27 | — | — | EP | disclosed |