SCHEMBL7688613

SCHEMBL7688613

N#CC(c1ccc(Cl)cc1)c1ncc(C(F)(F)F)cc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 1.00
ALDH1A1 P00352 2/20 0.81
PKM P14618 1/20 0.81
GAA P10253 4/20 0.75
MAPT P10636 4/20 0.60
LMNA P02545 3/20 0.60
KDM4E B2RXH2 1/20 0.60
HTT P42858 3/20 0.51
NPSR1 Q6W5P4 3/20 0.51
CYP2C9 P11712 2/20 0.51
CYP2C19 P33261 2/20 0.51
POLB P06746 2/20 0.51
CYP1A2 P05177 1/20 0.51
ATM Q13315 1/20 0.51
KMT2A Q03164 4/20 0.50
MEN1 O00255 3/20 0.50
CRHBP P24387 1/20 0.50
CRHR2 Q13324 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.49
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4961217 0.89 L3MBTL1 (0.81) L3MBTL1ALDH1A1PKMGAAMAPT
SCHEMBL7688112 0.79 KMT2A (0.76) L3MBTL1ALDH1A1PKMGAAMAPT
SCHEMBL18292261 0.78 L3MBTL1 (0.64) L3MBTL1ALDH1A1PKMGAAMAPT
SCHEMBL7692277 0.78 GAA (0.67) L3MBTL1ALDH1A1PKMGAAMAPT
SCHEMBL7688219 0.76 L3MBTL1 (0.61) L3MBTL1ALDH1A1PKMGAAMAPT
SCHEMBL14921128 0.76 L3MBTL1 (0.60) L3MBTL1ALDH1A1PKMGAAMAPT
Hydrochloric Acid SCHEMBL784570 0.74 L3MBTL1 (0.59) L3MBTL1ALDH1A1PKMGAAMAPT
SCHEMBL7691426 0.74 L3MBTL1 (0.58) L3MBTL1ALDH1A1PKMGAALMNA
SCHEMBL7687680 0.73 L3MBTL1 (0.58) L3MBTL1ALDH1A1PKMGAAMAPT
SCHEMBL7394115 0.73 L3MBTL1 (0.57) L3MBTL1ALDH1A1PKMGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6337305-B1 HERBICIDES FOR AGRICULTURE BASF AKTIENGESELLSCHAFT (DE) 2002-01-08 US disclosed
EP-0968188-A1 SUBSTITUTED 2-BENZ(O)YLPYRIDINES, THEIR PREPARATION AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2000-01-05 EP disclosed
WO-1998042671-A1 SUBSTITUTED 2-BENZ(O)YLPYRIDINES, THEIR PREPARATION AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-10-01 WO disclosed