Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 1/20 | 0.58 |
| ▸ | GUSB | P08236 | 8/20 | 0.53 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7396027 | 0.87 | HPSE (0.49) | HPSEGUSBCHEK2MITFOPRM1 | |
| SCHEMBL7391080 | 0.86 | CHEK2 (0.48) | HPSECHEK2MAPTTP53SMN1; SMN2 | |
| SCHEMBL7386703 | 0.83 | CHEK2 (0.48) | CHEK2TP53KDM4EALDH1A1HPGD | |
| SCHEMBL7386529 | 0.82 | GUSB (0.57) | HPSEGUSBCHEK2KDM4EALDH1A1 | |
| SCHEMBL7389936 | 0.82 | KDM4E (0.62) | HPSEMAPTTP53SMN1; SMN2KDM4E | |
| SCHEMBL7394008 | 0.79 | NPBWR1 (0.58) | CHEK2MAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7486513 | 0.79 | HPSE (0.45) | HPSECHEK2MAPTTP53SMN1; SMN2 | |
| SCHEMBL7398358 | 0.79 | HPSE (0.57) | HPSECHEK2MAPTTP53SMN1; SMN2 | |
| SCHEMBL7389024 | 0.78 | AMY1A (0.54) | HPSEGUSBMAPTSMN1; SMN2KDM4E | |
| SCHEMBL7393557 | 0.78 | GUSB (0.79) | HPSEGUSBAMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132381-A1 | Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2001-09-12 | — | — | EP | claimed |
| WO-2001066526-A1 | ESTER DERIVATIVES OF DIMETHYLPROPIONIC ACID AND PHARMACETUICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2001-09-13 | — | — | WO | disclosed |
| EP-1132381-A1 | Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2001-09-12 | — | — | EP | disclosed |