Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2944736 | 0.83 | SLC6A2 (0.47) | SLC6A2FNTAFNTBADAM17GPR84 | |
| SCHEMBL27939140 | 0.80 | PBRM1 (0.45) | SLC6A2FNTAFNTBADAM17GPR84 | |
| SCHEMBL28450714 | 0.78 | GPR84 (0.43) | SLC6A2FNTAFNTBADAM17GPR84 | |
| SCHEMBL7609416 | 0.77 | SLC6A2 (0.41) | SLC6A2FNTAFNTBADAM17GABRP | |
| SCHEMBL6288556 | 0.75 | PBRM1 (0.49) | ADAM17GPR84KMT2AMEN1KDM4E | |
| SCHEMBL17866728 | 0.73 | PBRM1 (0.50) | ADAM17GPR84KMT2AMEN1KDM4E | |
| SCHEMBL7508029 | 0.72 | MEN1 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5174863 | 0.72 | PBRM1 (0.49) | ADAM17GPR84CTNNB1WNT3AKMT2A | |
| SCHEMBL5172407 | 0.72 | PBRM1 (0.49) | ADAM17GPR84CTNNB1WNT3AKMT2A | |
| SCHEMBL1810243 | 0.71 | ALDH1A1 (0.47) | ADAM17GPR84KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993011154-A1 | INHIBITORS OF THE CONVERSION OF BIG ENDOTHELIN TO ENDOTHELIN | BERLEX LABORATORIES, INC. (US) | 1993-06-10 | — | — | WO | disclosed |