Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.45 |
| ▸ | WNT3A | P56704 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17082801 | 0.88 | KDM4E (0.57) | DRD4L3MBTL1KDM4E | |
| SCHEMBL7383608 | 0.87 | DRD4 (0.41) | DRD4L3MBTL1KDM4EDRD2DRD3 | |
| SCHEMBL7391718 | 0.86 | DRD4 (0.47) | DRD4L3MBTL1KDM4ECTNNB1DRD2 | |
| SCHEMBL7387492 | 0.85 | DRD4 (0.47) | DRD4L3MBTL1KDM4EDRD2 | |
| SCHEMBL7390484 | 0.85 | DRD4 (0.54) | DRD4KCNH2L3MBTL1KDM4EDRD2 | |
| SCHEMBL7390338 | 0.85 | DRD2 (0.56) | DRD4KCNH2L3MBTL1KDM4ECTNNB1 | |
| SCHEMBL7390423 | 0.85 | DRD4 (0.47) | DRD4L3MBTL1KDM4EDRD2DRD3 | |
| SCHEMBL7389570 | 0.85 | DRD4 (0.54) | DRD4KCNH2L3MBTL1KDM4EDRD2 | |
| SCHEMBL7390321 | 0.84 | DRD4 (0.47) | DRD4L3MBTL1KDM4EDRD2 | |
| SCHEMBL7393279 | 0.84 | DRD4 (0.69) | DRD4KCNH2CTNNB1WNT3ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0873990-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | disclosed |