Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 5/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391718 | 0.86 | DRD4 (0.47) | DRD4L3MBTL1KDM4EDRD2HTR7 | |
| SCHEMBL7390484 | 0.85 | DRD4 (0.54) | DRD4L3MBTL1KDM4EDRD2HTR1A | |
| SCHEMBL7394247 | 0.85 | DRD4 (0.49) | DRD4L3MBTL1KDM4EDRD2DRD3 | |
| SCHEMBL7390338 | 0.85 | DRD2 (0.56) | DRD4L3MBTL1KDM4EDRD2HTR1A | |
| SCHEMBL7389570 | 0.85 | DRD4 (0.54) | DRD4L3MBTL1KDM4EDRD2HTR1A | |
| SCHEMBL7390664 | 0.84 | HTR1A (0.53) | DRD4L3MBTL1KDM4EDRD2HTR1A | |
| SCHEMBL7390493 | 0.84 | MAPT (0.61) | L3MBTL1DRD2HTR1AHTR2AHTR7 | |
| SCHEMBL7390501 | 0.84 | MAPT (0.61) | L3MBTL1DRD2HTR1AHTR2AHTR7 | |
| SCHEMBL7386508 | 0.84 | MAPT (0.61) | L3MBTL1DRD2HTR1AHTR2AHTR7 | |
| SCHEMBL7387492 | 0.82 | DRD4 (0.47) | DRD4L3MBTL1KDM4EDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0873990-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | disclosed |