SCHEMBL739468

SCHEMBL739468

NCCc1ccccc1S(=O)(=O)F

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 8/20 0.52
F2 P00734 2/20 0.46
TMPRSS4 Q9NRS4 2/20 0.46
TP53 P04637 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
TSHR P16473 1/20 0.46
HTR2A P28223 1/20 0.42
ELANE P08246 1/20 0.41
SLC6A2 P23975 1/20 0.41
HTR6 P50406 6/20 0.40
HRH1 P35367 1/20 0.39
HTR1A P08908 1/20 0.39
HTR1D P28221 1/20 0.39
HTR1B P28222 1/20 0.39
HTR1F P30939 1/20 0.39
HTR7 P34969 1/20 0.39
DRD3 P35462 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30009738 1.00 TAAR1 (0.52) TAAR1F2TMPRSS4TP53CYP1A2
Hydrochloric Acid SCHEMBL525033 0.98 TAAR1 (0.50) TAAR1F2TMPRSS4TP53CYP1A2
SCHEMBL6680949 0.83 TAAR1 (0.50) TAAR1HTR2ASLC6A2HTR6HRH1
SCHEMBL5149827 0.83 ELANE (0.44) TAAR1F2TMPRSS4TP53CYP1A2
SCHEMBL731097 0.82 TAAR1 (0.52) TAAR1CYP1A2CYP2D6HTR2ASLC6A2
SCHEMBL8337031 0.80 TAAR1 (0.50) TAAR1CYP1A2CYP2D6HTR2ASLC6A2
SCHEMBL1805940 0.80 TAAR1 (0.50) TAAR1CYP1A2HTR2ASLC6A2HTR6
Hydrochloric Acid SCHEMBL14157101 0.78 TAAR1 (0.48) TAAR1F2TMPRSS4CYP1A2CYP2D6
SCHEMBL4598969 0.78 TAAR1 (0.48) TAAR1HTR2ASLC6A2HTR6HRH1
SCHEMBL39171 0.78 TAAR1 (0.45) TAAR1F2HTR2ASLC6A2HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2565905-B1 Mass spectrometry assay for plasma-renin QUEST DIAGNOSTICS INVEST INC (US) 2015-12-30 EP claimed
WO-2013136277-A1 PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF CARDIOVASCULAR DISEASES UNIMARK REMEDIES LTD. (IN) 2013-09-19 WO claimed
EP-1858540-A2 STABILIZED COMPOSITIONS CONTAINING NATRIURETIC PEPTIDES Bio-Rad Laboratories, Inc. (US) 2007-11-28 EP claimed
WO-2006088624-A2 STABILIZED COMPOSITIONS CONTAINING NATRIURETIC PEPTIDES BIO-RAD LABORATORIES, INC. (US) 2006-08-24 WO claimed
US-20060183681-A1 Stabilized compositions containing natriuretic peptides BIO-RAD LABORATORIES, INC. (US) 2006-08-17 US claimed
EP-1421175-A4 POLYMER STABILIZED PROTEINASES MOUNTAIN VIEW PHARMACEUTICALS (US) 2004-12-08 EP claimed
EP-1421175-A2 POLYMER STABILIZED PROTEINASES Mountain View Pharmaceuticals, Inc. (US) 2004-05-26 EP claimed
US-20030012777-A1 Polymer conjugates of proteinases MOUNTAIN VIEW PHARMACEUTICALS, INC. 2003-01-16 US claimed
WO-2003002716-A2 POLYMER STABILIZED PROTEINASES MOUNTAIN VIEW PHARMACEUTICALS, INC. (US) 2003-01-09 WO claimed
US-12508311-B2 Fusion protein, and preparation method and use thereof SUN YAT-SEN UNIVERSITY (CN) 2025-12-30 US disclosed
US-12378543-B2 Compositions for hemolysis and coagulation regulation and stabilization of extracellular vesicles STRECK LLC (US) 2025-08-05 US disclosed
EP-4427588-A2 COMPOSITIONS FOR HEMOLYSIS AND COAGULATION REGULATION AND STABILIZATION OF EXTRACELLULAR VESICLES Streck LLC (US) 2024-09-11 EP disclosed
EP-3697209-B1 COMPOSITIONS FOR HEMOLYSIS AND COAGULATION REGULATION AND STABILIZATION OF EXTRACELLULAR VESICLES STRECK LLC (US) 2024-07-24 EP disclosed
CN-115119829-B Compositions for the modulation of haemolysis and coagulation of extracellular vesicles and stabilization 斯特雷克股份有限公司 2024-07-12 CN disclosed
WO-1997038013-A1 MODULATION OF MAMMALIAN TELOMERASE BY PEPTIDE NUCLEIC ACIDS THE UNIVERSITY OF TEXAS SYSTEM (US) 1997-10-16 WO disclosed
WO-1997015687-A1 TELOMERASE ACTIVITY ASSAYS GERON CORPORATION (US) 1997-05-01 WO disclosed
EP-0759074-A1 STABILIZING SOLUTIONS FOR PROTEINS AND PEPTIDES DADE INTERNATIONAL INC. (US) 1997-02-26 EP disclosed
WO-1997002836-A1 CLOSTRIDIUM DIFFICILE TOXINS AS MUCOSAL ADJUVANTS ORAVAX, INC. (US) 1997-01-30 WO disclosed
WO-1996040885-A2 β-SECRETASE, ANTIBODIES TO β-SECRETASE, AND ASSAYS FOR DETECTING β-SECRETASE INHIBITION ATHENA NEUROSCIENCES, INC. (US) 1996-12-19 WO disclosed
WO-1996027661-A1 STABILIZING SOLUTIONS FOR PROTEINS AND PEPTIDES DADE INTERNATIONAL INC. (US) 1996-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12508311-B2 Fusion protein, and preparation method and use thereof KRAS, LAMP2, NRAS TAAR1 4717/4885F2 3039/4885TMPRSS4 585/4885
US-20030012777-A1 Polymer conjugates of proteinases PRNP, PRSS3, PRSS1 TAAR1 4494/4885F2 1131/4885TMPRSS4 197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.