Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5759463 | 0.74 | TSHR (0.37) | POLBTSHRMAPTALDH1A1TP53 | |
| SCHEMBL7333144 | 0.74 | KDM4E (0.37) | POLBCYP3A4MAPTGAAALDH1A1 | |
| SCHEMBL505507 | 0.73 | HTR4 (0.41) | HTTPOLBTSHRCYP3A4MAPT | |
| SCHEMBL2944408 | 0.73 | HTR4 (0.50) | HTTPOLBTSHRCYP3A4HTR4 | |
| SCHEMBL1502018 | 0.70 | HTR4 (0.51) | HTR4HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL6823514 | 0.69 | CA1 (0.34) | CA1CA2CA9 | |
| SCHEMBL5316552 | 0.68 | HTR4 (0.47) | HTR4HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7333211 | 0.67 | HTR4 (0.46) | HTR4HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8948599 | 0.66 | CA1 (0.31) | CA1CA2CA9 | |
| SCHEMBL7411412 | 0.65 | HTT (0.34) | HTTPOLBTSHRCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502209-A | SIDE EFFECT REDUCTION, GASTROINTESTINAL | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1996-03-26 | — | — | US | disclosed |
| EP-0691341-A1 | Benzopyrancarboxamide derivatives, salt thereof, process for the preparation of same and use thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1996-01-10 | — | — | EP | disclosed |