Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395138 | 0.78 | CYP3A4 (0.56) | — | |
| SCHEMBL7393378 | 0.78 | TDP1 (0.55) | SMN1; SMN2 | |
| SCHEMBL2736265 | 0.78 | CYP3A4 (0.56) | — | |
| SCHEMBL7388588 | 0.78 | TDP1 (0.55) | SMN1; SMN2 | |
| SCHEMBL6446176 | 0.73 | ALDH1A1 (0.65) | MAPK1TSHRALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6446181 | 0.73 | ALDH1A1 (0.65) | MAPK1TSHRALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7429785 | 0.73 | MAPK1 (0.50) | MAPK1TSHRALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL18893485 | 0.72 | CYP3A4 (0.50) | — | |
| SCHEMBL5175905 | 0.72 | MAPK1 (0.76) | MAPK1TSHRALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL7206283 | 0.72 | MAPK1 (0.76) | MAPK1TSHRALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5905068-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1999-05-18 | — | — | US | disclosed |