Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 16/20 | 0.48 |
| ▸ | HTRA1 | Q92743 | 4/20 | 0.45 |
| ▸ | CTRC | Q99895 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405598 | 0.87 | HTRA1 (0.49) | ELANEHTRA1 | |
| SCHEMBL7399764 | 0.86 | HTRA1 (0.48) | ELANEHTRA1 | |
| SCHEMBL8994472 | 0.78 | ELANE (0.79) | ELANECTRC | |
| SCHEMBL9298822 | 0.77 | ELANE (0.43) | ELANECTRC | |
| SCHEMBL7284362 | 0.76 | ELANE (0.54) | ELANE | |
| SCHEMBL7399095 | 0.76 | ELANE (0.42) | ELANEHTRA1CTRC | |
| SCHEMBL9298601 | 0.74 | ELANE (0.49) | ELANE | |
| SCHEMBL7402411 | 0.74 | HTRA1 (0.50) | ELANEHTRA1 | |
| SCHEMBL7398314 | 0.74 | HTRA1 (0.37) | ELANEHTRA1 | |
| SCHEMBL9298731 | 0.73 | ELANE (0.49) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636142-A1 | LACTAM PEPTIDES HAVING HLE INHIBITING ACTIVITY | ZENECA LIMITED (GB) | 1995-02-01 | — | — | EP | disclosed |
| WO-1993021209-A1 | LACTAM PEPTIDES HAVING HLE INHIBITING ACTIVITY | ZENECA LIMITED (GB) | 1993-10-28 | — | — | WO | disclosed |