Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 18/20 | 0.42 |
| ▸ | CTRC | Q99895 | 4/20 | 0.38 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402200 | 0.94 | ELANE (0.42) | ELANECTRCHTRA1 | |
| SCHEMBL7398314 | 0.82 | HTRA1 (0.37) | ELANEHTRA1 | |
| SCHEMBL9298822 | 0.81 | ELANE (0.43) | ELANECTRC | |
| SCHEMBL7274210 | 0.78 | ELANE (0.41) | ELANECTRC | |
| SCHEMBL7394151 | 0.77 | KDM4E (0.35) | HTRA1 | |
| SCHEMBL8536332 | 0.77 | ELANE (0.71) | ELANECTRC | |
| SCHEMBL7395403 | 0.76 | ELANE (0.48) | ELANECTRCHTRA1 | |
| SCHEMBL8994502 | 0.75 | ELANE (0.65) | ELANECTRC | |
| SCHEMBL7548502 | 0.72 | ELANE (0.71) | ELANECTRC | |
| SCHEMBL7502510 | 0.70 | P2RX7 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636142-A1 | LACTAM PEPTIDES HAVING HLE INHIBITING ACTIVITY | ZENECA LIMITED (GB) | 1995-02-01 | — | — | EP | disclosed |
| WO-1993021209-A1 | LACTAM PEPTIDES HAVING HLE INHIBITING ACTIVITY | ZENECA LIMITED (GB) | 1993-10-28 | — | — | WO | disclosed |