Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTRA1 | Q92743 | 16/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402411 | 0.88 | HTRA1 (0.50) | HTRA1ELANE | |
| SCHEMBL7395403 | 0.86 | ELANE (0.48) | HTRA1ELANE | |
| SCHEMBL7402422 | 0.85 | CMA1 (0.44) | HTRA1ELANE | |
| SCHEMBL9298830 | 0.83 | ELANE (0.51) | ELANE | |
| SCHEMBL7405598 | 0.82 | HTRA1 (0.49) | HTRA1ELANE | |
| SCHEMBL8994556 | 0.77 | ELANE (0.68) | ELANE | |
| SCHEMBL9298563 | 0.76 | ELANE (0.51) | HTRA1ELANE | |
| SCHEMBL7398168 | 0.73 | HTRA1 (0.36) | HTRA1ELANE | |
| SCHEMBL7305642 | 0.73 | ELANE (0.45) | ELANE | |
| SCHEMBL9298731 | 0.72 | ELANE (0.49) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636142-A1 | LACTAM PEPTIDES HAVING HLE INHIBITING ACTIVITY | ZENECA LIMITED (GB) | 1995-02-01 | — | — | EP | disclosed |
| WO-1993021209-A1 | LACTAM PEPTIDES HAVING HLE INHIBITING ACTIVITY | ZENECA LIMITED (GB) | 1993-10-28 | — | — | WO | disclosed |