Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 3/20 | 0.55 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.53 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.53 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505080 | 0.82 | GRIN2B (0.59) | CCR3CARM1PRMT6PRMT3PRMT1 | |
| SCHEMBL7653401 | 0.82 | GBA1 (0.37) | CCR3CARM1PRMT6GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL5974096 | 0.81 | GRIN2B (0.58) | CCR3CARM1PRMT6PRMT3PRMT1 | |
| SCHEMBL8248176 | 0.79 | CCR3 (0.63) | CCR3CARM1PRMT6PRMT3PRMT1 | |
| SCHEMBL918100 | 0.76 | CCR3 (0.63) | CCR3CARM1PRMT6PRMT3PRMT1 | |
| SCHEMBL13588754 | 0.75 | CCR3 (0.58) | CCR3CARM1PRMT6PRMT3PRMT1 | |
| SCHEMBL4632689 | 0.75 | CARM1 (0.53) | CCR3CARM1PRMT6PRMT3PRMT1 | |
| SCHEMBL7248849 | 0.73 | CCR3 (0.73) | CCR3CARM1PRMT6PRMT3PRMT1 | |
| SCHEMBL5969423 | 0.73 | CCR3 (0.67) | CCR3CARM1PRMT6PRMT3PRMT1 | |
| SCHEMBL10222790 | 0.72 | CCR3 (0.55) | CCR3CARM1PRMT6PRMT3PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189886-A1 | ETHANESULFONYL-PIPERIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000075109-A1 | ETHANESULFONYL-PIPERIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-14 | — | — | WO | disclosed |