Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 3/20 | 0.55 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.53 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8248176 | 0.79 | CCR3 (0.63) | CCR3PRMT6CARM1PRMT3PRMT1 | |
| SCHEMBL13588754 | 0.75 | CCR3 (0.58) | CCR3PRMT6CARM1PRMT3PRMT1 | |
| SCHEMBL918100 | 0.74 | CCR3 (0.63) | CCR3PRMT6CARM1PRMT3PRMT1 | |
| SCHEMBL5505080 | 0.72 | GRIN2B (0.59) | CCR3PRMT6CARM1PRMT3PRMT1 | |
| SCHEMBL7395591 | 0.72 | CCR3 (0.55) | CCR3PRMT6CARM1PRMT3PRMT1 | |
| SCHEMBL26213680 | 0.72 | PRMT6 (0.50) | CCR3PRMT6CARM1PRMT3PRMT1 | |
| SCHEMBL7403790 | 0.72 | CCR3 (1.00) | CCR3PRMT6CARM1PRMT3PRMT1 | |
| SCHEMBL7403436 | 0.72 | CCR3 (0.75) | CCR3PRMT6CARM1PRMT3PRMT1 | |
| Hydrochloric Acid SCHEMBL5974096 | 0.72 | GRIN2B (0.58) | CCR3PRMT6CARM1PRMT3PRMT1 | |
| SCHEMBL543919 | 0.70 | PRMT6 (1.00) | CCR3PRMT6CARM1PRMT3PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160116482-A1 | Target Binding Molecules Identified by Kinetic Target-Guided Synthesis | THE PENN STATE RESEARCH FOUNDATION (US) | 2016-04-28 | — | — | US | disclosed |
| US-20160116482-A1 | Target Binding Molecules Identified by Kinetic Target-Guided Synthesis | THE PENN STATE RESEARCH FOUNDATION (US) | 2016-04-28 | — | — | US | disclosed |
| US-20130203709-A1 | ACYLSULFONAMIDES AND PROCESSES FOR PRODUCING THE SAME | THE PENN STATE RESEARCH FOUNDATION (US) | 2013-08-08 | — | — | US | disclosed |
| US-20130203709-A1 | ACYLSULFONAMIDES AND PROCESSES FOR PRODUCING THE SAME | THE PENN STATE RESEARCH FOUNDATION (US) | 2013-08-08 | — | — | US | disclosed |
| WO-2012021486-A2 | ACYLSULFONAMIDES AND PROCESSES FOR PRODUCING THE SAME | UNIVERSITY OF SOUTH FLORIDA (US) | 2012-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160116482-A1 | Target Binding Molecules Identified by Kinetic Target-Guided Synthesis | MCL1, BCL2L1, BCL2L2 | CCR3 4739/4885PRMT6 3819/4885CARM1 4408/4885 |
| US-20130203709-A1 | ACYLSULFONAMIDES AND PROCESSES FOR PRODUCING THE SAME | BCL2, BCL2L2, BCL6 | CCR3 4849/4885PRMT6 1856/4885CARM1 4204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.