Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 17/20 | 0.47 |
| ▸ | MMP1 | P03956 | 9/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7388232 | 0.87 | MMP3 (0.47) | MMP3MMP1MMP2LNPEP | |
| SCHEMBL7431835 | 0.86 | MMP3 (0.51) | MMP3MMP1MMP2 | |
| SCHEMBL7481373 | 0.84 | MMP3 (0.51) | MMP3MMP1MMP2 | |
| SCHEMBL7358596 | 0.79 | MMP3 (0.46) | MMP3MMP1CA1CA2MMP2 | |
| SCHEMBL7366301 | 0.78 | MMP3 (0.47) | MMP3MMP1MMP2LNPEP | |
| SCHEMBL8902722 | 0.78 | MMP3 (0.46) | MMP3MMP1MMP2LNPEP | |
| SCHEMBL7359871 | 0.77 | MMP3 (0.44) | MMP3MMP1MMP2 | |
| SCHEMBL7365474 | 0.77 | MMP3 (0.42) | MMP3MMP1CA1CA2MMP2 | |
| SCHEMBL8895406 | 0.76 | MMP3 (0.52) | MMP3MMP1MMP2 | |
| SCHEMBL7358551 | 0.73 | MMP3 (0.56) | MMP3MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025949-A1 | SUBSTITUTED 5-AMINO-1,3,4-THIADIAZOLE-2-THIONES | PROSCRIPT, INC. (US) | 1998-06-18 | — | — | WO | disclosed |
| EP-0845002-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1998-06-03 | — | — | EP | disclosed |
| US-5677282-A | ENZYME INHIBITOR; OSTEOARTHRITIS AND RHEUMATIC DISORDERS | PROSCRIPT, INC. (US) | 1997-10-14 | — | — | US | disclosed |
| WO-1996040745-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1996-12-19 | — | — | WO | disclosed |