Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 9/20 | 0.52 |
| ▸ | MMP1 | P03956 | 4/20 | 0.51 |
| ▸ | HRAS | P01112 | 6/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431835 | 0.88 | MMP3 (0.51) | MMP3MMP1HRASMMP2HDAC8 | |
| SCHEMBL7481373 | 0.85 | MMP3 (0.51) | MMP3MMP1HRASMMP2HDAC8 | |
| SCHEMBL7358551 | 0.83 | MMP3 (0.56) | MMP3MMP1MMP2HDAC8 | |
| SCHEMBL7365138 | 0.81 | ITGB3 (0.57) | HRASHDAC8ITGB3ITGA2B | |
| SCHEMBL8896527 | 0.80 | MMP3 (0.57) | MMP3MMP1MMP2HDAC8 | |
| SCHEMBL7358578 | 0.79 | MMP3 (0.56) | MMP3MMP1MMP2HDAC8 | |
| SCHEMBL7394276 | 0.78 | MMP3 (0.55) | MMP3MMP1MMP2HDAC8ITGB3 | |
| SCHEMBL6964283 | 0.78 | MMP3 (0.65) | MMP3MMP1MMP2 | |
| SCHEMBL6964276 | 0.78 | MMP3 (0.65) | MMP3MMP1MMP2 | |
| SCHEMBL7388232 | 0.78 | MMP3 (0.47) | MMP3MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677282-A | ENZYME INHIBITOR; OSTEOARTHRITIS AND RHEUMATIC DISORDERS | PROSCRIPT, INC. (US) | 1997-10-14 | — | — | US | disclosed |