Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.45 |
| ▸ | F2 | P00734 | 4/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 3/20 | 0.39 |
| ▸ | PYGM | P11217 | 3/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4083313 | 0.85 | F10 (0.54) | F10F2 | |
| SCHEMBL4093550 | 0.85 | F10 (0.54) | F10F2 | |
| SCHEMBL743656 | 0.85 | F10 (0.56) | F10F2 | |
| Hydrochloric Acid SCHEMBL741709 | 0.82 | F10 (0.43) | F10F2CYP51A1SMYD3 | |
| SCHEMBL740197 | 0.79 | SMYD3 (0.51) | CYP51A1SMYD3PYGLPYGM | |
| SCHEMBL743187 | 0.78 | F10 (0.46) | F10CYP51A1SMYD3PYGLNAMPT | |
| SCHEMBL741602 | 0.77 | F10 (0.46) | F10F2CYP51A1SMYD3PYGL | |
| SCHEMBL4114513 | 0.77 | F10 (0.58) | F10F2 | |
| SCHEMBL743192 | 0.75 | F10 (0.46) | F10F2CYP51A1SMYD3PYGL | |
| SCHEMBL2933877 | 0.74 | F10 (0.53) | F10F2SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431370-B1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI SANKYO CO LTD (JP) | 2013-06-19 | — | — | EP | disclosed |
| EP-2431370-A1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-7935824-B2 | Ethylenediamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2011-05-03 | — | — | US | disclosed |