Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.46 |
| ▸ | CYP51A1 | Q16850 | 3/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PYGL | P06737 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL743192 | 0.86 | F10 (0.46) | F10CYP51A1SMYD3PYGLNAMPT | |
| SCHEMBL743187 | 0.85 | F10 (0.46) | F10CYP51A1SMYD3KMT2APYGL | |
| SCHEMBL740197 | 0.82 | SMYD3 (0.51) | CYP51A1SMYD3PYGL | |
| SCHEMBL743656 | 0.78 | F10 (0.56) | F10F2 | |
| SCHEMBL739574 | 0.77 | F10 (0.45) | F10CYP51A1SMYD3PYGLNAMPT | |
| SCHEMBL740465 | 0.76 | HRH4 (0.48) | F10CYP51A1SMYD3PYGLF2 | |
| SCHEMBL3336718 | 0.73 | F10 (0.63) | F10SMYD3 | |
| SCHEMBL3336715 | 0.73 | F10 (0.63) | F10SMYD3 | |
| SCHEMBL2940528 | 0.73 | F10 (0.63) | F10SMYD3 | |
| SCHEMBL29082311 | 0.73 | KMT2A (0.55) | F10CYP51A1SMYD3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431370-A1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-7935824-B2 | Ethylenediamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2011-05-03 | — | — | US | disclosed |