Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL451478 | 0.92 | CYP19A1 (0.41) | CYP19A1FFAR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28248440 | 0.88 | CYP19A1 (0.46) | CYP19A1FFAR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL536176 | 0.84 | FFAR1 (0.44) | CYP19A1FFAR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30129807 | 0.84 | FFAR1 (0.44) | CYP19A1FFAR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28248935 | 0.84 | CYP19A1 (0.46) | CYP19A1FFAR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3629719 | 0.81 | LIPG (0.53) | LIPGTSHR | |
| SCHEMBL3164765 | 0.81 | LIPG (0.53) | LIPGTSHR | |
| SCHEMBL6956286 | 0.81 | LIPG (0.53) | LIPGTSHR | |
| SCHEMBL6952873 | 0.81 | NAAA (0.46) | FFAR1MAPTKDM4ETSHRFAAH | |
| SCHEMBL6961355 | 0.81 | NAAA (0.46) | FFAR1MAPTKDM4ETSHRFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646183-A | Phenyl amidine alkanoic acids useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-07-08 | — | — | US | disclosed |
| US-5612355-A | Phenyl amidine lactones useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-03-18 | — | — | US | disclosed |
| US-5504106-A | Phenyl amidine alkanoic acids and lactones useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1996-04-02 | — | — | US | disclosed |
| WO-1994000424-A1 | PHENYL AMIDINE ALKANOIC ACIDS AND LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-06 | — | — | WO | disclosed |