Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.63 |
| ▸ | HPGD | P15428 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | F2 | P00734 | 2/20 | 0.63 |
| ▸ | F10 | P00742 | 1/20 | 0.56 |
| ▸ | F7 | P08709 | 1/20 | 0.56 |
| ▸ | F3 | P13726 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL913374 | 0.78 | ALDH1A1 (1.00) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL14571456 | 0.76 | F2 (0.65) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL914639 | 0.75 | ALDH1A1 (0.64) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7387892 | 0.73 | ALDH1A1 (0.70) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7394044 | 0.72 | KDM4E (0.62) | ALDH1A1HPGDSMN1; SMN2KMT2AF2 | |
| SCHEMBL913427 | 0.72 | F7 (0.72) | ALDH1A1HPGDF2F10F7 | |
| SCHEMBL914532 | 0.71 | F7 (1.00) | ALDH1A1HPGDMEN1KMT2AF2 | |
| SCHEMBL915806 | 0.70 | HSD17B10 (0.67) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8059748 | 0.70 | HSD17B10 (0.66) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL3354495 | 0.70 | ELANE (0.56) | ALDH1A1MEN1KMT2AF2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000030646-A1 | HETEROCYCLIC COMPOUNDS REGULATING CLOTTING | NOVO NORDISK A/S (DK) | 2000-06-02 | — | — | WO | claimed |