Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | F10 | P00742 | 1/20 | 0.54 |
| ▸ | F7 | P08709 | 1/20 | 0.54 |
| ▸ | F3 | P13726 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 4/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | XPO1 | O14980 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2301620 | 0.78 | ELANE (0.59) | ELANEF2F10F7F3 | |
| SCHEMBL1484086 | 0.78 | F2 (0.50) | ELANEF2F10F7F3 | |
| SCHEMBL26438943 | 0.78 | F2 (0.50) | ELANEF2F10F7F3 | |
| SCHEMBL6519360 | 0.76 | ELANE (0.61) | ELANEF2F10F7F3 | |
| SCHEMBL5265537 | 0.75 | F2 (0.50) | ELANEF2F10F7F3 | |
| SCHEMBL14571456 | 0.75 | F2 (0.65) | ELANEF2F10F7F3 | |
| SCHEMBL5110242 | 0.74 | ELANE (0.62) | ELANEF2F10F7F3 | |
| SCHEMBL4933414 | 0.74 | TDP2 (0.46) | ELANEF2F10F7F3 | |
| SCHEMBL316306 | 0.73 | KDM4E (0.53) | KDM4EALDH1A1NPC1L3MBTL1 | |
| SCHEMBL12351984 | 0.72 | ELANE (0.41) | ELANEKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9783537-B2 | 3-(4-ethylnylphenyl) pyridopyrimidinone compounds and process for preparation thereof useful as potential anticancer agents | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-10-10 | — | — | US | claimed |
| US-20160222006-A1 | 3-(4-Ethylnylphenyl) Pyridopyrimidinone Compounds and Process for Preparation Thereof Useful As Potential Anticancer Agents | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-04 | — | — | US | claimed |
| US-9783537-B2 | 3-(4-ethylnylphenyl) pyridopyrimidinone compounds and process for preparation thereof useful as potential anticancer agents | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-10-10 | — | — | US | disclosed |
| US-9783537-B2 | 3-(4-ethylnylphenyl) pyridopyrimidinone compounds and process for preparation thereof useful as potential anticancer agents | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-10-10 | — | — | US | disclosed |
| US-9783537-B2 | 3-(4-ethylnylphenyl) pyridopyrimidinone compounds and process for preparation thereof useful as potential anticancer agents | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-10-10 | — | — | US | disclosed |
| US-20160222006-A1 | 3-(4-Ethylnylphenyl) Pyridopyrimidinone Compounds and Process for Preparation Thereof Useful As Potential Anticancer Agents | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-04 | — | — | US | disclosed |
| US-20160222006-A1 | 3-(4-Ethylnylphenyl) Pyridopyrimidinone Compounds and Process for Preparation Thereof Useful As Potential Anticancer Agents | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-04 | — | — | US | disclosed |
| US-20160222006-A1 | 3-(4-Ethylnylphenyl) Pyridopyrimidinone Compounds and Process for Preparation Thereof Useful As Potential Anticancer Agents | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-04 | — | — | US | disclosed |
| US-20160108038-A1 | BICYCLIC ARYL SULFIDE AND ARYL SULFOXIDE DERIVATIVES AS PEST CONTROL AGENT | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-04-21 | — | — | US | disclosed |
| US-20160108038-A1 | BICYCLIC ARYL SULFIDE AND ARYL SULFOXIDE DERIVATIVES AS PEST CONTROL AGENT | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-04-21 | — | — | US | disclosed |
| US-20160108038-A1 | BICYCLIC ARYL SULFIDE AND ARYL SULFOXIDE DERIVATIVES AS PEST CONTROL AGENT | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-04-21 | — | — | US | disclosed |
| US-6638944-B2 | Have urea containing substituent at 1-position; induce biosynthesis of cytokines such as interferon and tumor necrosis factor, exhibit antiviral and antitumor properties | 3M INNOVATIVE PROPERTIES COMPANY | 2003-10-28 | — | — | US | disclosed |
| US-6624172-B2 | Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor, and useful as viricides and antitumor agents | 3M INNOVATIVE PROPERTIES COMPANY | 2003-09-23 | — | — | US | disclosed |
| US-20030096998-A1 | Imidazonaphtyridines | 3M INNOVATIVE PROPERTIES COMPANY | 2003-05-22 | — | — | US | disclosed |
| US-20030083500-A1 | Imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY | 2003-05-01 | — | — | US | disclosed |
| US-6518280-B2 | Antiviral and antitumor properties; immunomodulators and for inducing cytokine biosynthesis in animals | 3M INNOVATIVE PROPERTIES COMPANY | 2003-02-11 | — | — | US | disclosed |
| US-6514985-B1 | Induce the biosynthesis of cytokines such as interferon and tumor necrosis factor; exhibit antiviral and antitumor properties | 3M INNOVATIVE PROPERTIES COMPANY | 2003-02-04 | — | — | US | disclosed |
| US-20020173653-A1 | Imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY | 2002-11-21 | — | — | US | disclosed |
| US-20020173654-A1 | Imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY | 2002-11-21 | — | — | US | disclosed |
| US-6194425-B1 | VIRICIDES, ANTITUMOR AGENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2001-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083500-A1 | Imidazonaphthyridines | IFNG, IRF3, IFNAR1 | ELANE 1151/4885F2 3576/4885F10 3128/4885 |
| US-20030096998-A1 | Imidazonaphtyridines | IFNG, IRF3, IFNAR1 | ELANE 1210/4885F2 3739/4885F10 3168/4885 |
| US-20160108038-A1 | BICYCLIC ARYL SULFIDE AND ARYL SULFOXIDE DERIVATIVES AS PEST CONTROL AGENT | AADAC, AHR, ARSA | ELANE 4004/4885F2 2128/4885F10 2664/4885 |
| US-20160222006-A1 | 3-(4-Ethylnylphenyl) Pyridopyrimidinone Compounds and Process for Preparation Thereof Useful As Potential Anticancer Agents | CBR3, HCCS, CYP3A4 | ELANE 4854/4885F2 3458/4885F10 4024/4885 |
| US-20020173653-A1 | Imidazonaphthyridines | IFNG, IRF3, IFNAR1 | ELANE 1151/4885F2 3576/4885F10 3128/4885 |
| US-20020173654-A1 | Imidazonaphthyridines | IFNG, IRF3, IFNAR1 | ELANE 1151/4885F2 3576/4885F10 3128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.