SCHEMBL7396367

SCHEMBL7396367

CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)OCCCc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 17/20 1.00
MTOR P42345 1/20 0.75
FKBP4 Q02790 1/20 0.75
FKBP5 Q13451 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5834555 1.00 FKBP1A (1.00) FKBP1AMTORFKBP4FKBP5
SCHEMBL3426604 0.97 FKBP1A (1.00) FKBP1AMTORFKBP4FKBP5
SCHEMBL5966142 0.91 FKBP1A (1.00) FKBP1AMTORFKBP4FKBP5
SCHEMBL4678705 0.90 FKBP1A (0.82) FKBP1AMTORFKBP4FKBP5
SCHEMBL5965941 0.89 FKBP1A (1.00) FKBP1AMTORFKBP4FKBP5
SCHEMBL8099641 0.88 FKBP1A (1.00) FKBP1AMTORFKBP4FKBP5
SCHEMBL4680565 0.87 FKBP1A (0.78) FKBP1A
SCHEMBL3148722 0.87 FKBP1A (0.82) FKBP1AMTORFKBP4FKBP5
SCHEMBL7400429 0.87 FKBP1A (1.00) FKBP1A
SCHEMBL7424656 0.86 FKBP1A (0.80) FKBP1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376517-B1 FOR TREATING VISION LOSS, PREVENTING VISION DEGENERATION, AND PROMOTING VISION REGENERATION (?NEOPSIS?) GPI NIL HOLDINGS, INC. 2002-04-23 US disclosed