Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 10/20 | 0.48 |
| ▸ | PNP | P00491 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7396558 | 0.80 | HPRT1 (0.46) | HPRT1PNPALDH1A1KDM4ELMNA | |
| SCHEMBL7398061 | 0.77 | OPRK1 (0.47) | LMNA | |
| SCHEMBL7374581 | 0.74 | HPRT1 (0.64) | HPRT1PNP | |
| SCHEMBL7389719 | 0.73 | HPRT1 (0.47) | HPRT1PNP | |
| SCHEMBL3060815 | 0.73 | HPRT1 (0.63) | HPRT1PNP | |
| SCHEMBL7684892 | 0.70 | HPRT1 (0.67) | HPRT1PNP | |
| SCHEMBL7397072 | 0.70 | HPRT1 (0.59) | HPRT1PNP | |
| SCHEMBL7396839 | 0.70 | HPRT1 (0.48) | HPRT1PNPPOLB | |
| SCHEMBL11258920 | 0.70 | HPRT1 (0.69) | HPRT1PNP | |
| SCHEMBL7397889 | 0.69 | MAPK1 (0.49) | HPRT1PNPALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522082-B1 | MULTI-FUNCTIONAL PHARMACEUTICAL COMPOUNDS AND METHODS OF USE | GLASKY ALVIN J (US) | 1997-07-02 | — | — | EP | disclosed |
| EP-0522082-A4 | MULTI-FUNCTIONAL PHARMACEUTICAL COMPOUNDS AND METHODS OF USE | — | 1993-06-09 | — | — | EP | disclosed |
| EP-0522082-A1 | MULTI-FUNCTIONAL PHARMACEUTICAL COMPOUNDS AND METHODS OF USE. | GLASKY ALVIN J (US) | 1993-01-13 | — | — | EP | disclosed |
| US-5091432-A | Synergistic | SPECTRUM PHARMACEUTICALS, INC. | 1992-02-25 | — | — | US | disclosed |
| WO-1991014434-A1 | MULTI-FUNCTIONAL PHARMACEUTICAL COMPOUNDS AND METHODS OF USE | GLASKY ALVIN J (US) | 1991-10-03 | — | — | WO | disclosed |