Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.41 |
| ▸ | ITGAL | P20701 | 1/20 | 0.41 |
| ▸ | SLC6A12 | P48065 | 7/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 6/20 | 0.36 |
| ▸ | SLC6A13 | Q9NSD5 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631434 | 0.72 | ITGB1 (0.48) | ITGB3ITGB2ITGB1ITGAVITGA2B | |
| SCHEMBL4288132 | 0.72 | — | — | |
| SCHEMBL10642729 | 0.67 | TP53 (0.56) | ITGB3ITGB2ITGB1ITGAVITGA2B | |
| SCHEMBL8149190 | 0.64 | ITGB1 (0.41) | ITGB3ITGB2ITGB1ITGAVITGA2B | |
| SCHEMBL273409 | 0.64 | ITGB1 (0.41) | ITGB3ITGB2ITGB1ITGAVITGA2B | |
| SCHEMBL4979634 | 0.64 | ITGB1 (0.50) | ITGB3ITGB2ITGB1ITGAVITGA2B | |
| SCHEMBL10642674 | 0.63 | TP53 (0.62) | ITGB3ITGB2ITGB1ITGAVITGA2B | |
| SCHEMBL7414681 | 0.63 | TP53 (0.62) | ITGB3ITGB2ITGB1ITGAVITGA2B | |
| SCHEMBL6271481 | 0.63 | ITGB1 (0.39) | ITGB3ITGB2ITGB1ITGAVITGA2B | |
| SCHEMBL11042273 | 0.63 | ITGB3 (0.39) | ITGB3ITGB2ITGB1ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189873-A1 | EXCITATORY AMINO ACID RECEPTOR MODULATORS | Lilly, S.A. (ES) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000075101-A1 | EXCITATORY AMINO ACID RECEPTOR MODULATORS | LILLY, S.A. (ES) | 2000-12-14 | — | — | WO | disclosed |