Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.50 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.50 |
| ▸ | ITGAV | P06756 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.50 |
| ▸ | ITGAL | P20701 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15602681 | 0.82 | FOLH1 (0.43) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL28048806 | 0.82 | MAP3K14 (0.39) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL11872852 | 0.82 | GLA (0.40) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL19585667 | 0.80 | CRBN (0.58) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL24885110 | 0.79 | TDP1 (0.40) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL28479332 | 0.77 | MAP3K14 (0.50) | MAP3K14CRBNDDB1GLAMAPT | |
| SCHEMBL24885111 | 0.76 | ABL1 (0.47) | TSHRL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL5779882 | 0.76 | — | — | |
| SCHEMBL19839455 | 0.76 | — | — | |
| SCHEMBL2915829 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486998-A | Dipolyethylene glycol-insulin conjugate and preparation method and application thereof | 中山大学 | 2024-02-02 | — | — | CN | claimed |
| CN-118742317-A | Liver targeting substances and uses thereof | 韩美药品株式会社 | 2024-10-01 | — | — | CN | disclosed |
| CN-117615775-A | Therapeutic uses comprising combinations of triple agonists that are all active on glucagon, GLP-1 and GIP receptors | 韩美药品株式会社 | 2024-02-27 | — | — | CN | disclosed |
| CN-117486998-A | Dipolyethylene glycol-insulin conjugate and preparation method and application thereof | 中山大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-117486998-A | Dipolyethylene glycol-insulin conjugate and preparation method and application thereof | 中山大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-117462693-A | XTEN conjugate compositions and methods of making the same | 阿穆尼克斯运营公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-117427179-A | Chemical modifier of human urinary kallidinogenase | 江苏艾迪药业股份有限公司 | 2024-01-23 | — | — | CN | disclosed |
| US-11834553-B2 | Alkoxylation methods | NEKTAR THERAPEUTICS (US) | 2023-12-05 | — | — | US | disclosed |
| CN-116635055-A | Pharmaceutical composition for preventing or treating lupus-related diseases comprising GIP derivative or long-acting conjugate thereof | 韩美药品株式会社 | 2023-08-22 | — | — | CN | disclosed |
| CN-116583533-A | GIP derivative, long-acting conjugate thereof and pharmaceutical composition comprising the same | 韩美药品株式会社 | 2023-08-11 | — | — | CN | disclosed |
| US-6881396-B2 | Stabilization of radiopharmaceutical compositions using hydrophilic 6-hydroxy-chromans | DIATIDE, INC. (US) | 2005-04-19 | — | — | US | disclosed |
| US-20040058984-A1 | Stabilization of radiopharmaceutical compositions using hydrophilic thioethers and hydrophilic 6-hydroxy chromans | DIATIDE LABORATORIES | 2004-03-25 | — | — | US | disclosed |
| EP-1381397-A2 | STABILISATION OF RADIOPHARMACEUTICAL COMPOSITIONS USING A HYDROPHILIC THIOETHER OR A HYDROPHILIC 6-HYDROXY CHROMAN | Diatide, Inc. (US) | 2004-01-21 | — | — | EP | disclosed |
| EP-0804252-B1 | MONOAMINE, DIAMIDE, THIOL-CONTAINING METAL CHELATING AGENTS | DIATIDE INC (US) | 2003-08-13 | — | — | EP | disclosed |
| US-20030103895-A1 | Stabilization of radiopharmaceutical compositions using hydrophilic thioethers and hydrophilic 6-hydroxy chromans | CIS BIO INTERNATIONAL (FR) | 2003-06-05 | — | — | US | disclosed |
| US-20030103899-A1 | Stabilization of radiopharmaceutical compositions using hydrophilic 6-hydroxy-chromans | CIS BIO INTERNATIONAL (FR) | 2003-06-05 | — | — | US | disclosed |
| US-20030072709-A1 | Stabilization of radiopharmaceutical compositions using hydrophilic thioethers | CIS BIO INTERNATIONAL (FR) | 2003-04-17 | — | — | US | disclosed |
| WO-2002060491-A2 | STABILIZATION OF RADIOPHARMACEUTICAL COMPOSITIONS USING A HYDROPHILIC THIOETHER OR A HYDROPHILIC 6-HYDROXY CHROMAN | DIATIDE, INC. (US) | 2002-08-08 | — | — | WO | disclosed |
| EP-0804252-A2 | MONOAMINE, DIAMIDE, THIOL-CONTAINING METAL CHELATING AGENTS | DIATECH, INC. (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1995033497-A1 | MONOAMINE, DIAMIDE, THIOL-CONTAINING METAL CHELATING AGENTS | DIATECH, INC. (US) | 1995-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030072709-A1 | Stabilization of radiopharmaceutical compositions using hydrophilic thioethers | TTPA, TTR, PHOSPHO1 | ITGB1 2936/4885ITGA5 3968/4885ITGB3 2560/4885 |
| US-20030103895-A1 | Stabilization of radiopharmaceutical compositions using hydrophilic thioethers and hydrophilic 6-hydroxy chromans | TSHR, SHBG, SLC18A1 | ITGB1 3260/4885ITGA5 3768/4885ITGB3 2261/4885 |
| US-20040058984-A1 | Stabilization of radiopharmaceutical compositions using hydrophilic thioethers and hydrophilic 6-hydroxy chromans | HTR6, SLC7A1, HTR7 | ITGB1 3034/4885ITGA5 3132/4885ITGB3 2055/4885 |
| US-11834553-B2 | Alkoxylation methods | ALK, ALKBH3, SLC10A1 | ITGB1 4315/4885ITGA5 3110/4885ITGB3 2880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.