Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | FAAH | O00519 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TNF | P01375 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.52 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8268109 | 0.89 | PTGDR2 (0.53) | KDM4EGAAPTGDR2HPGDHSD17B10 | |
| SCHEMBL8268110 | 0.88 | FAAH (0.54) | KDM4EGAAPTGDR2HPGDHSD17B10 | |
| SCHEMBL4175599 | 0.87 | KDM4E (0.66) | KDM4EGAAPTGDR2HPGDHSD17B10 | |
| SCHEMBL16421862 | 0.86 | GAA (0.59) | KDM4EGAAPTGDR2HPGDHSD17B10 | |
| SCHEMBL4180937 | 0.86 | KDM4E (0.65) | KDM4EGAAPTGDR2HPGDHSD17B10 | |
| SCHEMBL22965159 | 0.84 | KDM4E (0.69) | KDM4EHPGDHSD17B10ALDH1A1HTT | |
| SCHEMBL22965212 | 0.82 | PTGDR2 (0.59) | KDM4EGAAPTGDR2HPGDHSD17B10 | |
| SCHEMBL7397143 | 0.82 | SIRT2 (0.60) | KDM4EGAAPTGDR2HPGDALDH1A1 | |
| SCHEMBL22965259 | 0.82 | PTGDR2 (0.63) | KDM4EGAAPTGDR2HPGDHSD17B10 | |
| SCHEMBL22965246 | 0.82 | PTGDR2 (0.54) | KDM4EGAAPTGDR2HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021023796-A1 | COMPOSITIONS FOR TRANSFECTING A NUCLEIC ACID MOLECULE INTO A CELL COMPRISING HETEROCYCLIC COMPOUNDS GRAFTED TO A CATIONIC POLYMER, AND THEIR APPLICATIONS | POLYPLUS TRANSFECTION (FR) | 2021-02-11 | — | — | WO | disclosed |