Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.69 |
| ▸ | PLAU | P00749 | 4/20 | 0.69 |
| ▸ | PLAT | P00750 | 4/20 | 0.69 |
| ▸ | PLG | P00747 | 3/20 | 0.64 |
| ▸ | KLK8 | O60259 | 2/20 | 0.63 |
| ▸ | KLK4 | Q9Y5K2 | 2/20 | 0.63 |
| ▸ | F10 | P00742 | 1/20 | 0.63 |
| ▸ | KLK2 | P20151 | 1/20 | 0.63 |
| ▸ | ELANE | P08246 | 2/20 | 0.59 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.59 |
| ▸ | ECE1 | P42892 | 5/20 | 0.57 |
| ▸ | MME | P08473 | 4/20 | 0.57 |
| ▸ | KLK1 | P06870 | 2/20 | 0.57 |
| ▸ | ANPEP | P15144 | 1/20 | 0.57 |
| ▸ | LAP3 | P28838 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403534 | 0.88 | F2 (0.86) | F2PLAUPLATPLGKLK8 | |
| SCHEMBL7397375 | 0.86 | ECE1 (0.59) | F2PLAUPLATECE1MME | |
| SCHEMBL7328702 | 0.85 | ECE1 (0.63) | F2PLAUPLATPLGECE1 | |
| SCHEMBL14334539 | 0.85 | ECE1 (0.63) | F2PLAUPLATPLGECE1 | |
| SCHEMBL7291199 | 0.83 | ECE1 (0.61) | F2PLAUPLATECE1MME | |
| SCHEMBL2249441 | 0.82 | PLAU (1.00) | F2PLAUPLATPLGKLK8 | |
| SCHEMBL8197773 | 0.81 | ECE1 (0.61) | F2PLAUPLATECE1MME | |
| SCHEMBL8200922 | 0.81 | ECE1 (0.57) | F2PLAUPLATECE1MME | |
| SCHEMBL16856590 | 0.80 | ECE1 (0.58) | F2PLAUPLATECE1MME | |
| SCHEMBL28101997 | 0.80 | ECE1 (0.58) | F2PLAUPLATECE1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504070-A | ADMINISTERING OLIGOPEPTIDES, PHOSPHONATES AND MODIFIED AMINO ACIDS AS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1996-04-02 | — | — | US | claimed |
| WO-1993011154-A1 | INHIBITORS OF THE CONVERSION OF BIG ENDOTHELIN TO ENDOTHELIN | BERLEX LABORATORIES, INC. (US) | 1993-06-10 | — | — | WO | claimed |
| US-5504070-A | ADMINISTERING OLIGOPEPTIDES, PHOSPHONATES AND MODIFIED AMINO ACIDS AS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1996-04-02 | — | — | US | disclosed |
| WO-1993011154-A1 | INHIBITORS OF THE CONVERSION OF BIG ENDOTHELIN TO ENDOTHELIN | BERLEX LABORATORIES, INC. (US) | 1993-06-10 | — | — | WO | disclosed |