Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.86 |
| ▸ | PLAU | P00749 | 8/20 | 0.86 |
| ▸ | PLAT | P00750 | 8/20 | 0.86 |
| ▸ | PLG | P00747 | 7/20 | 0.79 |
| ▸ | KLK8 | O60259 | 3/20 | 0.78 |
| ▸ | KLK4 | Q9Y5K2 | 3/20 | 0.78 |
| ▸ | F10 | P00742 | 3/20 | 0.78 |
| ▸ | KLK2 | P20151 | 2/20 | 0.78 |
| ▸ | ELANE | P08246 | 2/20 | 0.67 |
| ▸ | KLK1 | P06870 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.60 |
| ▸ | MME | P08473 | 2/20 | 0.58 |
| ▸ | ECE1 | P42892 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2249441 | 0.93 | PLAU (1.00) | F2PLAUPLATPLGKLK8 | |
| SCHEMBL12354625 | 0.90 | F2 (0.75) | F2PLAUPLATPLGKLK8 | |
| SCHEMBL12354626 | 0.89 | PLAU (1.00) | F2PLAUPLATPLGKLK8 | |
| SCHEMBL5881673 | 0.88 | ELANE (0.70) | F2PLAUPLATPLGKLK8 | |
| SCHEMBL7397171 | 0.88 | F2 (0.69) | F2PLAUPLATPLGKLK8 | |
| SCHEMBL17126273 | 0.87 | PLAU (0.78) | F2PLAUPLATPLGKLK8 | |
| SCHEMBL2247009 | 0.85 | F2 (0.68) | F2PLAUPLATPLGKLK8 | |
| SCHEMBL7397132 | 0.85 | F2 (0.65) | F2PLAUPLATPLGKLK8 | |
| SCHEMBL9971041 | 0.84 | PLAU (0.75) | F2PLAUPLATPLGKLK8 | |
| SCHEMBL14334539 | 0.83 | ECE1 (0.63) | F2PLAUPLATPLGMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504070-A | ADMINISTERING OLIGOPEPTIDES, PHOSPHONATES AND MODIFIED AMINO ACIDS AS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1996-04-02 | — | — | US | disclosed |
| WO-1993011154-A1 | INHIBITORS OF THE CONVERSION OF BIG ENDOTHELIN TO ENDOTHELIN | BERLEX LABORATORIES, INC. (US) | 1993-06-10 | — | — | WO | disclosed |