Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7390354 | 0.92 | PRMT1 (0.51) | NPC1RAB9ATDP1LMNAKMT2A | |
| SCHEMBL7397210 | 0.89 | MEN1 (0.56) | NPC1RAB9ATDP1LMNAMAPT | |
| SCHEMBL7390973 | 0.89 | ENPP1 (0.53) | NPC1RAB9AHSD17B10MMP2MMP3 | |
| SCHEMBL7394824 | 0.88 | TRPV1 (0.50) | NPC1RAB9AMMP2CYP1A2LMNA | |
| SCHEMBL7399956 | 0.88 | NPC1 (0.51) | NPC1RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL7392377 | 0.87 | MEN1 (0.47) | NPC1RAB9AMMP2MMP3MMP13 | |
| SCHEMBL7428930 | 0.87 | KMT2A (0.51) | RAB9AMMP13ALDH1A1KDM4ELMNA | |
| SCHEMBL7493288 | 0.84 | RAB9A (0.51) | NPC1RAB9AHSD17B10TDP1MMP2 | |
| SCHEMBL7392495 | 0.84 | ENPP1 (0.50) | HSD17B10MMP2MMP3MMP13MAPT | |
| SCHEMBL7393966 | 0.84 | KCNQ3 (0.51) | NPC1RAB9ATDP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006215-A1 | 3-ARYLSULFONYL-2-HYDROXY-2-METHYLPROPANOIC ACID DERIVATES | PHARMACIA ITALIA S.P.A. (IT) | 2002-01-24 | — | — | WO | claimed |
| WO-2002006215-A1 | 3-ARYLSULFONYL-2-HYDROXY-2-METHYLPROPANOIC ACID DERIVATES | PHARMACIA ITALIA S.P.A. (IT) | 2002-01-24 | — | — | WO | disclosed |