Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.52 |
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 5/20 | 0.51 |
| ▸ | CTSL | P07711 | 5/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.49 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.49 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735268 | 1.00 | CTSK (0.52) | CTSKSYKCTSSCTSLCTSB | |
| SCHEMBL29361609 | 0.91 | SIRT2 (0.58) | CTSKSIRT1SIRT2 | |
| SCHEMBL8430542 | 0.91 | PPARA (0.55) | CTSKSYKCTSSCTSLCTSB | |
| SCHEMBL8431546 | 0.91 | PPARA (0.55) | CTSKSYKCTSSCTSLCTSB | |
| SCHEMBL7904398 | 0.90 | CTSK (0.51) | CTSKSYKCTSSCTSLCTSB | |
| SCHEMBL30902868 | 0.90 | CTSK (0.51) | CTSKSYKCTSSCTSLCTSB | |
| SCHEMBL9819558 | 0.90 | SYK (0.55) | CTSKSYKCTSSCTSLCTSB | |
| SCHEMBL13570900 | 0.90 | SYK (0.55) | CTSKSYKCTSSCTSLCTSB | |
| SCHEMBL13570899 | 0.90 | SYK (0.55) | CTSKSYKCTSSCTSLCTSB | |
| SCHEMBL5971174 | 0.90 | PPARA (0.55) | CTSKSYKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420427-B1 | PREVENTION AND/OR TREATMENT OF RHEUMATOID DISEASES, ARTHROSTEITIS, UNUSUAL BONE RESORPTION, OSTEOPOROSIS, PERIODONTITIS, INTERSTITIAL NEPHRITIS, ARTERIOSCLEROSIS, PULMONARY EMPHYSEMA, CIRRHOSIS, CORNEA INJURY | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1024134-A1 | AMINOBUTANOIC ACID DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-08-02 | — | — | EP | disclosed |
| EP-0634998-B1 | HYDROXAMIC ACID BASED COLLAGENASE AND CYTOKINE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 1997-03-19 | — | — | EP | disclosed |
| US-5525629-A | HYDROXAMIC ACID DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1996-06-11 | — | — | US | disclosed |
| EP-0634998-A1 | HYDROXAMIC ACID BASED COLLAGENASE AND CYTOKINE INHIBITORS. | BRITISH BIO TECHNOLOGY (GB) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993020047-A1 | HYDROXAMIC ACID BASED COLLAGENASE AND CYTOKINE INHIBITORS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-10-14 | — | — | WO | disclosed |