Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 6/20 | 0.50 |
| ▸ | CTSS | P25774 | 5/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.49 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.49 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30902868 | 0.96 | CTSK (0.51) | CTSKSYKCTSLCTSSCTSB | |
| SCHEMBL13570899 | 0.95 | SYK (0.55) | CTSKSYKCTSLCTSSCTSB | |
| SCHEMBL13570900 | 0.95 | SYK (0.55) | CTSKSYKCTSLCTSSCTSB | |
| SCHEMBL9819558 | 0.95 | SYK (0.55) | CTSKSYKCTSLCTSSCTSB | |
| SCHEMBL30480137 | 0.93 | CTSK (0.60) | CTSKCTSLCTSSCTSBPSMB5 | |
| SCHEMBL9819550 | 0.93 | CTSK (0.63) | CTSKCTSLCTSSCTSBPSMB5 | |
| SCHEMBL29100712 | 0.92 | SIRT2 (0.55) | CTSLCTSS | |
| SCHEMBL29100713 | 0.92 | SIRT2 (0.55) | CTSLCTSS | |
| SCHEMBL8722981 | 0.91 | CTSK (0.53) | CTSKSYKCTSLCTSSCTSB | |
| SCHEMBL19325104 | 0.91 | SYK (0.51) | CTSKSYKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6319702-B1 | NUCLEOTIDE SEQUENCS CODING AN ENZYMATIC POLYPEPTIDE AND CELL TARGETING COMPOUND; FOR USE IN TREATMENT OF CANCER | GLAXO WELLCOME, INC. | 2001-11-20 | — | — | US | disclosed |