Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 15/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 4/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394771 | 0.91 | MMP3 (0.55) | MMP3ALDH1A1LMNAMMP2MMP1 | |
| SCHEMBL7398823 | 0.87 | MMP3 (0.43) | MMP3MMP2MMP8 | |
| SCHEMBL7397726 | 0.81 | MMP3 (0.50) | MMP3ALDH1A1LMNAMMP2MMP1 | |
| SCHEMBL7402167 | 0.80 | MMP3 (0.59) | MMP3MMP2MMP1 | |
| SCHEMBL7396368 | 0.78 | MMP3 (0.54) | MMP3MMP2 | |
| SCHEMBL7432765 | 0.77 | LMNA (0.40) | MMP3ALDH1A1LMNAMMP2CHRNB2 | |
| SCHEMBL7397284 | 0.77 | MMP3 (0.40) | MMP3MMP2MMP1 | |
| SCHEMBL7398821 | 0.73 | MMP3 (0.40) | MMP3MMP2MMP1 | |
| SCHEMBL8858187 | 0.72 | MMP3 (0.40) | MMP3ALDH1A1LMNAMMP2MMP1 | |
| SCHEMBL7401524 | 0.71 | MMP3 (0.66) | MMP3MMP2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623143-A1 | SUBSTITUTED PHOSPHINIC ACID-CONTAINING PEPTIDYL DERIVATIVES AS ANTIDEGENERATIVE AGENTS | MERCK & CO. INC. (US) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014112-A1 | SUBSTITUTED PHOSPHINIC ACID-CONTAINING PEPTIDYL DERIVATIVES AS ANTIDEGENERATIVE AGENTS | MERCK & CO., INC. (US) | 1993-07-22 | — | — | WO | disclosed |