Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.48 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335243 | 0.94 | AVPR2 (0.48) | AVPR2AVPR1A | |
| SCHEMBL7339651 | 0.91 | AVPR2 (0.51) | AVPR2AVPR1A | |
| SCHEMBL7333346 | 0.86 | LMNA (0.44) | LMNATP53 | |
| SCHEMBL7344491 | 0.86 | TP53 (0.40) | TP53SHMT2 | |
| SCHEMBL7334278 | 0.84 | AVPR2 (0.43) | AVPR2AVPR1A | |
| SCHEMBL7343236 | 0.84 | AVPR2 (0.45) | AVPR2AVPR1A | |
| SCHEMBL7368892 | 0.83 | AVPR2 (0.56) | AVPR2AVPR1A | |
| SCHEMBL7334645 | 0.83 | AVPR2 (0.49) | AVPR2AVPR1A | |
| SCHEMBL7334184 | 0.82 | TP53 (0.47) | TP53AVPR2AVPR1ASHMT2 | |
| SCHEMBL5739209 | 0.81 | AVPR2 (0.59) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022282-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | claimed |