Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334278 | 0.92 | AVPR2 (0.43) | — | |
| SCHEMBL7335243 | 0.92 | AVPR2 (0.48) | — | |
| SCHEMBL7343290 | 0.86 | — | — | |
| SCHEMBL7334422 | 0.86 | TP53 (0.41) | TP53MAPTSHMT2 | |
| SCHEMBL7397457 | 0.86 | LMNA (0.49) | TP53SHMT2 | |
| SCHEMBL7345166 | 0.85 | TP53 (0.44) | TP53MAPT | |
| SCHEMBL7343236 | 0.85 | AVPR2 (0.45) | — | |
| SCHEMBL7342280 | 0.85 | MEN1 (0.47) | TP53 | |
| SCHEMBL7345315 | 0.84 | TP53 (0.40) | TP53MAPT | |
| SCHEMBL7333346 | 0.84 | LMNA (0.44) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022282-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |