Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 3/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.32 |
| ▸ | MMP2 | P08253 | 3/20 | 0.31 |
| ▸ | MMP3 | P08254 | 3/20 | 0.31 |
| ▸ | MMP9 | P14780 | 3/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397475 | 1.00 | LCK (0.37) | LCKFYNDAOSLC1A3SLC1A2 | |
| SCHEMBL7391939 | 0.76 | FFAR1 (0.52) | MTNR1AMTNR1BMMP2MMP3MMP9 | |
| SCHEMBL7391935 | 0.76 | FFAR1 (0.52) | MTNR1AMTNR1BMMP2MMP3MMP9 | |
| SCHEMBL7218149 | 0.74 | FFAR1 (0.55) | LCKFYNDAOCES2CES1 | |
| SCHEMBL12276603 | 0.71 | ALDH1A1 (0.46) | LCKFYNDAOCES2CES1 | |
| SCHEMBL11437310 | 0.70 | MMP2 (0.50) | MMEMTNR1AMTNR1BMMP2MMP3 | |
| SCHEMBL7393328 | 0.70 | MME (0.39) | SLC1A3SLC1A2SLC1A1MMEPTGS1 | |
| SCHEMBL9240332 | 0.70 | MME (0.39) | SLC1A3SLC1A2SLC1A1MMEPTGS1 | |
| SCHEMBL2683009 | 0.69 | MME (0.49) | LCKFYNDAOSLC1A3SLC1A2 | |
| SCHEMBL10170676 | 0.69 | MME (0.49) | LCKFYNDAOSLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535042-B1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1995-03-29 | — | — | EP | disclosed |
| US-5348978-A | Angiotensin converting enzyme inhibitors | FISONS PLC (GB) | 1994-09-20 | — | — | US | disclosed |
| EP-0535042-A1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS. | FISONS PLC (GB) | 1993-04-07 | — | — | EP | disclosed |
| WO-1992000276-A2 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1992-01-09 | — | — | WO | disclosed |