Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.48 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL123068 | 0.93 | CA1 (0.67) | CA1CA2CA12CA7CA9 | |
| SCHEMBL1115036 | 0.79 | CA1 (0.56) | CA1CA2CA12CA7CA9 | |
| SCHEMBL32662867 | 0.79 | CA12 (0.67) | CA1CA2CA12CA7CA9 | |
| SCHEMBL1058422 | 0.79 | CA12 (0.67) | CA1CA2CA12CA7CA9 | |
| SCHEMBL6100118 | 0.78 | ABL1 (0.70) | CA1CA2CA12CA7CA9 | |
| SCHEMBL11295587 | 0.78 | KDM4E (0.62) | CA1CA2CA12CA7CA9 | |
| SCHEMBL1995650 | 0.77 | ABL1 (0.64) | CA1CA2CA12CA7CA9 | |
| SCHEMBL16960600 | 0.77 | ABL1 (0.64) | CA1CA2CA12CA7CA9 | |
| SCHEMBL267531 | 0.77 | ABL1 (0.74) | ABL1KDM4EALDH1A1TSHRNR4A2 | |
| SCHEMBL4363906 | 0.77 | ABL1 (0.62) | ABL1LMNAKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017630-A9 | SUBSTITUTED BENZAMIDES AND RADIOLIGAND ANALOGS AND METHODS OF USE | — | 1996-08-08 | — | — | WO | disclosed |
| WO-1996017630-A1 | SUBSTITUTED BENZAMIDES AND RADIOLIGAND ANALOGS AND METHODS OF USE | VANDERBILT UNIVERSITY (US) | 1996-06-13 | — | — | WO | disclosed |