SCHEMBL267531

SCHEMBL267531

COC(=O)c1cc(Cl)ccc1N

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.74
KDM4E B2RXH2 6/20 0.62
ALDH1A1 P00352 5/20 0.62
GAA P10253 4/20 0.62
HSD17B10 Q99714 3/20 0.62
MAPT P10636 3/20 0.62
HPGD P15428 3/20 0.62
ALOX15 P16050 1/20 0.62
TSHR P16473 1/20 0.62
CFTR P13569 1/20 0.56
RECQL P46063 1/20 0.53
GLA P06280 1/20 0.51
CASP1 P29466 1/20 0.51
CASP7 P55210 1/20 0.51
ATM Q13315 1/20 0.51
SLC6A4 P31645 1/20 0.51
SLC6A3 Q01959 1/20 0.51
NR4A2 P43354 2/20 0.51
FADS1 O60427 1/20 0.51
NOS2 P35228 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4264458 0.86 ABL1 (0.61) ABL1KDM4EALDH1A1GAAHSD17B10
SCHEMBL771687 0.85 ABL1 (1.00) ABL1KDM4EALDH1A1GAAHSD17B10
SCHEMBL29009314 0.85 RECQL (0.56) ABL1KDM4EALDH1A1GAAHSD17B10
SCHEMBL17530348 0.84 BRAF (0.58) ABL1KDM4EALDH1A1GAAHSD17B10
SCHEMBL6100118 0.82 ABL1 (0.70) ABL1KDM4EALDH1A1GAAHSD17B10
SCHEMBL8208503 0.82 FADS1 (0.56) ABL1KDM4EALDH1A1GAARECQL
SCHEMBL6168887 0.81 GAA (0.66) ABL1KDM4EALDH1A1GAAHSD17B10
SCHEMBL7529190 0.81 KDM4E (0.66) ABL1KDM4EALDH1A1GAAHSD17B10
SCHEMBL4363906 0.81 ABL1 (0.62) ABL1KDM4EALDH1A1MAPTTSHR
SCHEMBL415970 0.81 ABL1 (0.50) ABL1KDM4EALDH1A1GAAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 533 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
US-20260138956-A1 NOVEL COMPOUNDS AND USES THEREOF RECURSION PHARMACEUTICALS INC (US) 2026-05-21 US disclosed
US-12606522-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives ORSOBIO, INC. (US) 2026-04-21 US disclosed
US-12600729-B2 New-type benzazepine fused ring derivative SHANGHAI JEYOU PHARMACEUTICAL CO., LTD. (CN) 2026-04-14 US disclosed
EP-4229055-B1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CRYPTOSPORIDIOSIS NOVARTIS AG (CH) 2026-03-04 EP disclosed
EP-4688756-A1 QUINAZOLINE DIONE COMPOUNDS AND USES THEREOF EDGEWISE THERAPEUTICS, INC. (US) 2026-02-11 EP disclosed
US-12528827-B2 Tricyclic heteroaryl-substituted quinoline and azaquinoline compounds as PAR4 inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2026-01-20 US disclosed
US-12509462-B2 3-(phenylsulfonyl)-[1,2,3]triazolo[1,5A]quinazolin-5(4H)-one derivatives BioVersys AG (CH) 2025-12-30 US disclosed
EP-4649086-A1 PROTEASE INHIBITORS FOR TREATING OR PREVENTING CORONAVIRUS INFECTION Merck Sharp & Dohme LLC (US) 2025-11-19 EP disclosed
EP-4622959-A1 2-AMINO-N-(4-AMINO-3,4-DIOXO-1-(2-OXOPYRROLIDIN-3-YL)BUTAN-2-YL)BENZAMIDE DERIVATIVES AS PROTEASE INHIBITORS FOR TREATING OR PREVENTING CORONAVIRUS INFECTION Merck Sharp & Dohme LLC (US) 2025-10-01 EP disclosed
US-3987026-A POLYESTERS CIBA-GEIGY CORPORATION (US) 1976-10-19 US disclosed
US-3971771-A DYES FOR POLYESTERS CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3971740-A DYES FOR POLYESTER FIBERS CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3964862-A Process for dyeing and printing textile materials of synthetic organic fibers CIBA-GEIGY AG (CH) 1976-06-22 US disclosed
US-3954398-A Polyester fibers dyed with a disazo disperse dyestuff CIBA-GEIGY AG (CH) 1976-05-04 US disclosed
US-3945991-A Heterocyclic azo compounds containing a quaternated hydrazide group CIBA-GEIGY AG (CH) 1976-03-23 US disclosed
US-3945989-A Fluoro triazine containing water insoluble azo dyestuff CIBA-GEIGY AG (CH) 1976-03-23 US disclosed
US-3943120-A WATER INSOLUBLE CIBA-GEIGY AG (CH) 1976-03-09 US disclosed
US-3933786-A Heterocyclic-azo-phenyl compounds containing a styrl group CIBA-GEIGY AG (CH) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138956-A1 NOVEL COMPOUNDS AND USES THEREOF SLC10A1, NR3C2, CYP2C8 ABL1 924/4885KDM4E 4053/4885ALDH1A1 230/4885
US-12606522-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives NR3C2, NR5A1, SRD5A2 ABL1 2031/4885KDM4E 3921/4885ALDH1A1 1507/4885
US-12509462-B2 3-(phenylsulfonyl)-[1,2,3]triazolo[1,5A]quinazolin-5(4H)-one derivatives CUTA, OR10J3, CCR10 ABL1 1317/4885KDM4E 4357/4885ALDH1A1 1420/4885
US-12600729-B2 New-type benzazepine fused ring derivative AVPR1B, AVPR2, AVPR1A ABL1 3113/4885KDM4E 3354/4885ALDH1A1 923/4885
US-12528827-B2 Tricyclic heteroaryl-substituted quinoline and azaquinoline compounds as PAR4 inhibitors F2RL3, F2R, PF4 ABL1 681/4885KDM4E 3061/4885ALDH1A1 1173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.