Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.72 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.72 |
| ▸ | ITGAV | P06756 | 2/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399432 | 0.85 | ITGB3 (0.62) | ITGB3ITGA2BITGAV | |
| Hydrochloric Acid SCHEMBL7488060 | 0.83 | ITGB3 (0.98) | ITGB3ITGA2BITGAV | |
| SCHEMBL7399205 | 0.81 | ITGB3 (0.84) | ITGB3ITGA2BITGAV | |
| SCHEMBL7399761 | 0.80 | ITGB3 (0.77) | ITGB3ITGA2BITGAV | |
| SCHEMBL7487559 | 0.80 | ITGB3 (0.76) | ITGB3ITGA2BITGAV | |
| SCHEMBL7398723 | 0.80 | ITGB3 (0.73) | ITGB3ITGA2BITGAV | |
| SCHEMBL7397770 | 0.79 | ITGB3 (0.69) | ITGB3ITGA2BITGAV | |
| SCHEMBL7398496 | 0.79 | ITGB3 (0.68) | ITGB3ITGA2BITGAV | |
| SCHEMBL7488462 | 0.79 | ITGB3 (0.72) | ITGB3ITGA2BITGAV | |
| SCHEMBL8458584 | 0.79 | ITGB3 (0.75) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648368-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1997-07-15 | — | — | US | disclosed |
| EP-0673247-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS. | MERCK & CO INC (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0673247-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994012181-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-09 | — | — | WO | disclosed |