Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | TNF | P01375 | 4/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397692 | 1.00 | NOD1 (0.46) | NOD1NPC1RAB9ATNFNOD2 | |
| SCHEMBL7394271 | 0.97 | ITGB3 (0.50) | NOD1NPC1RAB9ATNFNOD2 | |
| SCHEMBL7394269 | 0.97 | ITGB3 (0.50) | NOD1NPC1RAB9ATNFNOD2 | |
| SCHEMBL7435483 | 0.93 | NOD1 (0.47) | NOD1NPC1RAB9ATNFNOD2 | |
| SCHEMBL7435481 | 0.93 | NOD1 (0.47) | NOD1NPC1RAB9ATNFNOD2 | |
| SCHEMBL7386697 | 0.93 | ITGB3 (0.47) | NOD1NPC1RAB9ATNFNOD2 | |
| SCHEMBL7386699 | 0.93 | ITGB3 (0.47) | NOD1NPC1RAB9ATNFNOD2 | |
| SCHEMBL7393544 | 0.93 | ITGB3 (0.43) | NOD1NPC1RAB9ATNFNOD2 | |
| SCHEMBL7393542 | 0.93 | ITGB3 (0.43) | NOD1NPC1RAB9ATNFNOD2 | |
| SCHEMBL7395559 | 0.93 | ITGB3 (0.44) | NOD1NPC1RAB9ATNFNOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760364-B1 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI CHEMICALS INC (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-0760364-A2 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-03-05 | — | — | EP | disclosed |