Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 11/20 | 0.61 |
| ▸ | MMP1 | P03956 | 11/20 | 0.61 |
| ▸ | MMP2 | P08253 | 11/20 | 0.61 |
| ▸ | MMP9 | P14780 | 7/20 | 0.61 |
| ▸ | MMP7 | P09237 | 6/20 | 0.61 |
| ▸ | MMP14 | P50281 | 3/20 | 0.61 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 4/20 | 0.50 |
| ▸ | FCER2 | P06734 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402160 | 0.99 | MMP3 (0.60) | MMP3MMP1MMP2MMP9MMP7 | |
| SCHEMBL7403300 | 0.96 | MMP1 (0.60) | MMP3MMP1MMP2MMP9MMP7 | |
| SCHEMBL7397714 | 0.92 | MMP1 (0.55) | MMP3MMP1MMP2MMP9MMP7 | |
| SCHEMBL7404781 | 0.86 | MMP3 (0.58) | MMP3MMP1MMP2MMP9MMP7 | |
| SCHEMBL7381282 | 0.86 | MMP1 (0.58) | MMP3MMP1MMP2MMP9MMP7 | |
| SCHEMBL6416194 | 0.86 | MMP1 (0.58) | MMP3MMP1MMP2MMP9MMP7 | |
| SCHEMBL8764329 | 0.86 | MMP1 (0.58) | MMP3MMP1MMP2MMP9MMP7 | |
| SCHEMBL7897220 | 0.86 | MMP1 (0.56) | MMP3MMP1MMP2MMP9MMP7 | |
| SCHEMBL7593715 | 0.86 | MMP1 (0.57) | MMP3MMP1MMP2MMP9MMP7 | |
| SCHEMBL7427129 | 0.85 | MMP1 (0.58) | MMP3MMP1MMP2MMP9MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996035711-A1 | PEPTIDE COMPOUNDS WHICH INHIBIT METALLOPROTEINASE AND TNF LIBERATION, AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-14 | — | — | WO | claimed |