SCHEMBL7398013

SCHEMBL7398013

CCOC(=O)CCc1ccccc1OC(F)(F)F

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 3/20 0.60
CYP4A11 Q02928 3/20 0.60
EPHX2 P34913 2/20 0.47
ALDH1A1 P00352 1/20 0.47
GAA P10253 1/20 0.47
PPARG P37231 1/20 0.47
DRD2 P14416 4/20 0.44
SLC6A3 Q01959 4/20 0.44
APP P05067 1/20 0.44
POLB P06746 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
MAPT P10636 1/20 0.42
SLC6A2 P23975 1/20 0.42
VNN1 O95497 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16672732 0.92 CYP4F2 (0.57) CYP4F2CYP4A11EPHX2ALDH1A1PPARG
SCHEMBL16672593 0.91 CYP4F2 (0.63) CYP4F2CYP4A11EPHX2ALDH1A1PPARG
SCHEMBL6343659 0.85 PPARG (0.48) CYP4F2CYP4A11EPHX2PPARGAPP
SCHEMBL7687145 0.82 CYP4F2 (0.67) CYP4F2CYP4A11ALDH1A1GAAPOLB
SCHEMBL16673226 0.82 CYP4F2 (0.67) CYP4F2CYP4A11ALDH1A1GAASMN1; SMN2
SCHEMBL27624240 0.82 VNN1 (0.46) EPHX2GAAPPARGDRD2SLC6A3
SCHEMBL30670216 0.81 CYP4F2 (0.61) CYP4F2CYP4A11EPHX2ALDH1A1GAA
SCHEMBL69660 0.81 CYP4F2 (0.86) CYP4F2CYP4A11EPHX2ALDH1A1GAA
SCHEMBL30055829 0.80 FFAR1 (0.56) PPARGDRD2SLC6A3
SCHEMBL1508357 0.80 FFAR1 (0.56) PPARGDRD2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2869389-B1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTIC SOLUTION CELL USING SAME MITSUBISHI CHEM CORP (JP) 2019-11-13 EP disclosed
US-10320030-B2 Nonaqueous electrolyte solution and nonaqueous electrolyte battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2019-06-11 US disclosed
US-20150140448-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2015-05-21 US disclosed
EP-2869389-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTIC SOLUTION CELL USING SAME Mitsubishi Chemical Corporation (JP) 2015-05-06 EP disclosed
US-20140107135-A1 PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 AUSPEX PHARMACEUTICALS, INC. (US) 2014-04-17 US disclosed
WO-1996012697-A9 CALCIUM RECEPTOR-ACTIVE COMPOUNDS NPS PHARMA INC (US) 2000-08-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140107135-A1 PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 PLA2G1B, PLA2G4A, PLA2G4B CYP4F2 1213/4885CYP4A11 2315/4885EPHX2 454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.